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- aggregation classification "A1".
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2014".
- aggregation format "application/pdf".
- aggregation hasFormat 4384026.bibtex.
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- aggregation isPartOf urn:isbn:9780128000946.
- aggregation isPartOf urn:issn:0065-2423.
- aggregation language "eng".
- aggregation publisher "Elsevier Academic Press".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Vitamin D binding protein: a multifunctional protein of clinical importance".
- aggregation abstract "Since the discovery of group-specific component and its polymorphism by Hirschfeld in 1959, research has put spotlight on this multifunctional transport protein (vitamin D binding protein, DBP). Besides the transport of vitamin D metabolites, DBP is a plasma glycoprotein with many important functions, including sequestration of actin, modulation of immune and inflammatory responses, binding of fatty acids, and control of bone development. A considerable DBP polymorphism has been described with a specific allele distribution in different geographic area. Multiple studies have shed light on the interesting relationship between polymorphisms of the DBP gene and the susceptibility to diseases. In this review, we give an overview of the multifunctional character of DBP and describe the clinical importance of DBP and its polymorphisms. Finally, we discuss the possibilities to use DBP as a novel therapeutic agent.".
- aggregation authorList BK976807.
- aggregation endPage "57".
- aggregation startPage "1".
- aggregation volume "63".
- aggregation aggregates 5660826.
- aggregation isDescribedBy 4384026.
- aggregation similarTo B978-0-12-800094-6.00001-7.
- aggregation similarTo LU-4384026.