Matches in UGent Biblio for { <https://biblio.ugent.be/publication/4399970#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B447840.
- aggregation creator B447841.
- aggregation creator B447842.
- aggregation creator B447843.
- aggregation creator B447844.
- aggregation creator B447845.
- aggregation creator B447846.
- aggregation creator B447847.
- aggregation creator person.
- aggregation date "2014".
- aggregation format "application/pdf".
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- aggregation isPartOf urn:issn:0213-3911.
- aggregation language "eng".
- aggregation rights "I have retained and own the full copyright for this publication".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Infection through structured polymicrobial Gardnerella biofilms (StPM-GB)".
- aggregation abstract "BACKGROUND: We analysed data on bacterial vaginosis (BV) contradicting the paradigm of mono-infection. METHODOLOGY: Tissues and epithelial cells of vagina, uterus, fallopian tubes and perianal region were investigated using fluorescence in situ hybridization (FISH) in women with BV and controls. RESULTS: Healthy vagina was free of biofilms. Prolific structured polymicrobial (StPM) Gardnerella-dominated biofilm characterised BV. The intact StPM-Gardnerellabiofilm enveloped desquamated vaginal/prepuce epithelial cells and was secreted with urine and sperma. The disease involved both genders and occurred in pairs. Children born to women with BV were negative. Monotherapy with metronidazole, moxifloxacin or local antiseptics suppressed but often did not eradicate StPMGardnerella-biofilms. There was no BV without Gardnerella, but Gardnerella was not BV. Outside of StPM-biofilm, Gardnerella was also found in a subset of children and healthy adults, but was dispersed, temporal and did not transform into StPM-Gardnerella-biofilm. CONCLUSIONS: StPM-Gardnerella-biofilm is an infectious subject. The assembly of single players to StPM-Gardnerella-biofilm is a not trivial every day process, but probably an evolutionary event with a long history of growth, propagation and selection for viability and ability to reshape the environment. The evolutionary memory is cemented in the structural differentiation of StPM-Gardnerella-biofilms and imparts them to resist previous and emerging challenges.".
- aggregation authorList BK780593.
- aggregation endPage "587".
- aggregation issue "5".
- aggregation startPage "567".
- aggregation volume "29".
- aggregation aggregates 4399983.
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