Matches in UGent Biblio for { <https://biblio.ugent.be/publication/5806927#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B928588.
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- aggregation creator B928590.
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- aggregation date "2015".
- aggregation format "application/pdf".
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- aggregation isPartOf urn:issn:0148-639X.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Effects of tail suspension on serum testosterone and molecular targets regulating muscle mass".
- aggregation abstract "Introduction: The contribution of reduced testosterone levels to tail suspension (TS)-induced muscle atrophy remains equivocal. The molecular mechanism by which testosterone regulates muscle mass during TS has not been investigated. Methods: Effects of TS on serum testosterone levels, muscle mass, and expression of muscle atrophy- and hypertrophy-inducing targets were measured in soleus (SOL) and extensor digitorum longus (EDL) muscles following testosterone administration during 1, 5, and 14 days of TS in male mice. Results: TS produced an increase followed by a transient drop in testosterone levels. Muscle atrophy was associated with downregulation of Igf1 and upregulation of Mstn, Redd1, Atrogin-1, and MuRF1 mRNA with clear differences in Igf1, Mstn, and MAFbx/Atrogin-1 gene expression between SOL and EDL. Testosterone supplementation did not affect muscle mass or protein expression levels during TS. Discussion: The known anabolic effects of testosterone are not sufficient to ameliorate loss of muscle mass during TS".
- aggregation authorList BK1312507.
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- aggregation similarTo mus.24542.
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