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- aggregation classification "A1".
- aggregation creator B799355.
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- aggregation date "2015".
- aggregation format "application/pdf".
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- aggregation isPartOf urn:issn:0021-8561.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Agriculture and Food Sciences".
- aggregation title "Toward a new European threshold to disciminate illegally administered from naturally occurring thiouracil in livestock".
- aggregation abstract "Thiouracil, 1 (Figure 1) is a thyrostat inhibiting the thyroid function, resulting in fraudulent weight gain if applied in the fattening of livestock. The latter abuse is strictly forbidden and monitored in the European Union. Recently, endogenous sources of thiouracil were identified after frequently monitoring low-level thiouracil positive urine samples and a ‘recommend concentration’ (RC) of 10 µg/L was suggested by the EURL to facilitate decision-making. However, the systematic occurrence of urine samples exceeding the RC, led to demands for international surveys defining an epidemiologic threshold. Therefore, six European Member States (France, Poland, the Netherlands, United Kingdom, Norway and Belgium) have shared their official thiouracil data (2010-2012) collected from bovines, porcines and small livestock with 95 and 99 % percentiles of 8.1 and 18.2 µg/L for bovines (n = 3894); 7.4 and 13.5 µg/L for porcines (n = 654) and 7.4 µg/L (95% only) for small livestock (n = 85), respectively. Bovine percentiles decreased with the animal age (non-adults significantly higher levels for bovines) and higher levels were observed in male bovines compared to females.".
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- aggregation endPage "1346".
- aggregation issue "5".
- aggregation startPage "1339".
- aggregation volume "63".
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