Matches in UGent Biblio for { <https://biblio.ugent.be/publication/594760#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B502802.
- aggregation creator B502803.
- aggregation creator B502804.
- aggregation creator B502805.
- aggregation creator B502806.
- aggregation creator person.
- aggregation date "2008".
- aggregation format "application/pdf".
- aggregation hasFormat 594760.bibtex.
- aggregation hasFormat 594760.csv.
- aggregation hasFormat 594760.dc.
- aggregation hasFormat 594760.didl.
- aggregation hasFormat 594760.doc.
- aggregation hasFormat 594760.json.
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- aggregation hasFormat 594760.rdf.
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- aggregation hasFormat 594760.txt.
- aggregation hasFormat 594760.xls.
- aggregation hasFormat 594760.yaml.
- aggregation isPartOf urn:issn:0022-0795.
- aggregation language "eng".
- aggregation subject "Biology and Life Sciences".
- aggregation title "Physiological manipulation of cellular activity tunes protein and ultrastructural profiles in a neuroendocrine cell".
- aggregation abstract "To study in vivo the dynamics of the biosynthetic and secretory processes in a neuroendocrine cell, we use the proopiomelanocortin-producing intermediate pituitary melanotrope cells of Xenopus laevis. The activity of these cells can be simply manipulated by adapting the annual to a white or a black background, resulting in inactive and hyperactive cells respectively. Here, we applied differential display proteomics and field emission scanning electron microscopy (FESEM) to examine the changes in architecture accompanying the gradual transition of the inactive to the hyperactive melanotrope cells. The proteomic analysis showed differential expression of neuroendocrine secretory proteins, endoplasmic reticulum (ER)-resident chaperones, and housekeeping and metabolic proteins. The FESEM study revealed changes in the ultrastructure of the ER and Golgi and the number of secretory granules. We conclude that activation of neuroendocrine cells tunes their molecular machineries and organelles to become professional secretors.".
- aggregation authorList BK843017.
- aggregation endPage "616".
- aggregation startPage "607".
- aggregation volume "198".
- aggregation aggregates 598172.
- aggregation isDescribedBy 594760.
- aggregation similarTo JOE-08-0175.
- aggregation similarTo LU-594760.