Matches in UGent Biblio for { <https://biblio.ugent.be/publication/595637#aggregation> ?p ?o. }
Showing items 1 to 37 of
37
with 100 items per page.
- aggregation classification "A1".
- aggregation creator B383253.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2009".
- aggregation format "application/pdf".
- aggregation hasFormat 595637.bibtex.
- aggregation hasFormat 595637.csv.
- aggregation hasFormat 595637.dc.
- aggregation hasFormat 595637.didl.
- aggregation hasFormat 595637.doc.
- aggregation hasFormat 595637.json.
- aggregation hasFormat 595637.mets.
- aggregation hasFormat 595637.mods.
- aggregation hasFormat 595637.rdf.
- aggregation hasFormat 595637.ris.
- aggregation hasFormat 595637.txt.
- aggregation hasFormat 595637.xls.
- aggregation hasFormat 595637.yaml.
- aggregation isPartOf urn:issn:0741-5400.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Biology and Life Sciences".
- aggregation title "Inhibition of spontaneous neutrophil apoptosis by parabutoporin acts independently of NADPH oxidase inhibition but by lipid raft-dependent stimulation of Akt".
- aggregation abstract "Neutrophil cell death plays a crucial role in neutrophil homeostasis and the resolution of inflammation. The superoxide-producing NADPH oxidase is involved in pathogen degradation and subsequent activation of cell death programs. Neutrophils from patients with chronic granulomatous disease, who have a deficient NADPH oxidase activity, have been demonstrated previously to have a prolonged lifespan, suggesting that a basal NADPH oxidase activity also regulates spontaneous neutrophil turnover. The NADPH oxidase inhibitor parabutoporin (PP) does delay spontaneous apoptosis, but this effect is completely independent of NADPH oxidase inhibition. Instead, the prosurvival effect of PP depends on activation of protein kinase B/Akt via lipid raft signaling. Disruption of lipid rafts abrogates the prosurvival effect without interfering with NADPH oxidase activity. Furthermore, we cannot detect a different rate of spontaneous apoptosis between normal and NADPH oxidase-deficient neutrophils, arguing against a role of NADPH oxidase in spontaneous neutrophil apoptosis.".
- aggregation authorList BK692718.
- aggregation endPage "507".
- aggregation issue "3".
- aggregation startPage "497".
- aggregation volume "85".
- aggregation aggregates 2936645.
- aggregation isDescribedBy 595637.
- aggregation similarTo jlb.0908525.
- aggregation similarTo LU-595637.