Matches in UGent Biblio for { <https://biblio.ugent.be/publication/664587#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B410265.
- aggregation creator B410266.
- aggregation creator B410267.
- aggregation creator B410268.
- aggregation creator B410269.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2009".
- aggregation format "application/pdf".
- aggregation hasFormat 664587.bibtex.
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- aggregation hasFormat 664587.doc.
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- aggregation hasFormat 664587.txt.
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- aggregation isPartOf urn:issn:0009-9147.
- aggregation language "eng".
- aggregation subject "Chemistry".
- aggregation title "Toward standardization of insulin immunoassays".
- aggregation abstract "BACKGROUND: Measurement of circulating insulin may improve the classification and management of diabetes mellitus and assist in treating people with insulin resistance. METHODS: A work group convened by the American Diabetes Association evaluated results for a panel of 39 single donor sera measured by 10 commercial insulin methods from 9 manufactures against an isotope dilution-liquid chromatography/tandem mass spectrometry (IDMS) measurement procedure calibrated using purified recombinant insulin. We used a candidate primary (pure substance) reference material, pooled serum, and single donor sera to evaluate approaches to achieve improved agreement of results between the routine and reference measurement procedures. RESULTS: Four of 10 methods had >= 95% of individual serum results within 32% of the IDMS concentrations. However, the bias vs IDMS was more than 15.5% for 7 of 10 methods in 36%-100% of individual samples. A purified recombinant insulin preparation used as a common calibrator did not improve harmonization of results among routine methods but was not used as instructed by all participants. Calibration using serum pools achieved bias < 15.5% for nearly all results in the concentration range covered by the pools (> 60 pmol/L). Calibration using a panel of Individual sera was the most effective to improve harmonization of results over the full measuring range. CONCLUSIONS: Agreement among methods can be improved by establishing traceability to the IDMS procedure using a panel of native sera. Pooled sera may be useful as trueness control materials. The usefulness of the pure insulin primary reference material [candidate reference material for Insulin (cRMI)] requires clarification of protocols used by manufacturers.".
- aggregation authorList BK726787.
- aggregation endPage "1018".
- aggregation issue "5".
- aggregation startPage "1011".
- aggregation volume "55".
- aggregation aggregates 669992.
- aggregation isDescribedBy 664587.
- aggregation similarTo clinchem.2008.118380.
- aggregation similarTo LU-664587.