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- aggregation classification "A1".
- aggregation creator B355671.
- aggregation creator B355672.
- aggregation creator B355673.
- aggregation creator B355674.
- aggregation creator person.
- aggregation date "2008".
- aggregation format "application/pdf".
- aggregation hasFormat 690609.bibtex.
- aggregation hasFormat 690609.csv.
- aggregation hasFormat 690609.dc.
- aggregation hasFormat 690609.didl.
- aggregation hasFormat 690609.doc.
- aggregation hasFormat 690609.json.
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- aggregation hasFormat 690609.txt.
- aggregation hasFormat 690609.xls.
- aggregation hasFormat 690609.yaml.
- aggregation isPartOf urn:issn:0739-4462.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Agriculture and Food Sciences".
- aggregation title "Effects of RH-5992 on ecdysteroidogenesis of the prothoracic glands during the fourth larval instar of the silkworm, Bombyx mori".
- aggregation abstract "Stage-dependent effects of RH-5992 on ecdysteroidogenesis of the prothoracic glands during the fourth larval instar of the silkworm, Bombyx mori, were studied in the present report. When larvae were treated with RH-5992 during the early stages of the fourth larval instar (between day 0 and day 1), initially ecdysteroid levels in the hemolymph were inhibited. However, 24 h after RH-5992 application, ecdysteroid levels were greatly increased as compared with those treated with acetone. The examination of the in vitro prothoracic gland activity upon RH-5992 application during the early stages of the fourth larval instar confirmed a short-term inhibitory effect. When RH-5992 was applied to the later stages of the fourth larval instar, no effects on both hemolymph ecdysteroid levels and prothoracic gland activity were observed. Addition of RH-5992 to incubation medium strongly inhibited ecdysteroid secretion by the prothoracic glands from the early fourth instar, indicating direct action of RH-5992 on ecdysteroidogenesis by prothoracic glands. Four hours after application with RH-5992 on day 1.5, prothoracic glands still showed an activated response to PTTH in both PTTH-cAMP signaling and the extracellular signal-regulated kinase (IRK) signaling. Moreover, addition of RH-5992 to incubation medium did not interfere with the stimulatory effect of the glands to PTTH in ecdysteroidogenesis. These results indicated that both PTTH-cAMP signaling and PTTH-ERK signaling may not be involved in short-term inhibitory regulation by RH-5992.".
- aggregation authorList BK655700.
- aggregation endPage "205".
- aggregation issue "4".
- aggregation startPage "197".
- aggregation volume "68".
- aggregation aggregates 714253.
- aggregation isDescribedBy 690609.
- aggregation similarTo arch.20262.
- aggregation similarTo LU-690609.