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- 6906372 classification A1.
- 6906372 date "2015".
- 6906372 language "eng".
- 6906372 type journalArticle.
- 6906372 hasPart 6906376.pdf.
- 6906372 subject "Medicine and Health Sciences".
- 6906372 doi "10.1093/femsec/fiv054".
- 6906372 issn "0168-6496".
- 6906372 issue "6".
- 6906372 volume "91".
- 6906372 abstract "Butyrate-producing bacteria are promising probiotic candidates to target microbial dysbiosis in gastrointestinal disorders like inflammatory bowel diseases. Butyricicoccus pullicaecorum 25-3(T), a butyrate-producing clostridial cluster IV strain, is such a candidate. Little is known about its abundance in the colon microbiota and its butyrogenic properties. We used the M-SHIME (R), an in vitro simulator for the human intestinal microbial ecosystem, to study the effect of supplementing a single dose of B. pullicaecorum 25-3(T) on lumen-and mucus-associated microbiota of eight individuals. Butyricicoccus pullicaecorum was more abundant in mucus-associated microbiota compared with lumen microbiota. Supplementation with a single dose of B. pullicaecorum 25-3(T) resulted in a temporary increase in B. pullicaecorum bacteria in lumen compartment of all individuals. In two cases, the responders, an increased butyrate production was observed as compared with the control. 16S rRNA gene amplicon sequencing revealed the microbiota of responders to be different as compared to non-responder microbiota. We can conclude that B. pullicaecorum 25-3(T) is a mucus-associated bacterium whose potency to stimulate butyrate production is characterized by a large interindividual variability in terms of composition of the receiving microbial community.".
- 6906372 author 09CD5E80-F0EE-11E1-A9DE-61C894A0A6B4.
- 6906372 author 16AF6E86-F0EE-11E1-A9DE-61C894A0A6B4.
- 6906372 author 5B9712DC-6CC3-11E2-9EA0-5E6B10BDE39D.
- 6906372 author DD586EC0-FF80-11E1-9705-E1D010BDE39D.
- 6906372 author F3EBA27A-F0ED-11E1-A9DE-61C894A0A6B4.
- 6906372 author F56DD06E-F0ED-11E1-A9DE-61C894A0A6B4.
- 6906372 author F5BC232C-F0ED-11E1-A9DE-61C894A0A6B4.
- 6906372 author F5D28EA0-F0ED-11E1-A9DE-61C894A0A6B4.
- 6906372 author F5FDB080-F0ED-11E1-A9DE-61C894A0A6B4.
- 6906372 author F8E8386A-F0ED-11E1-A9DE-61C894A0A6B4.
- 6906372 author F986D77C-F0ED-11E1-A9DE-61C894A0A6B4.
- 6906372 author urn:uuid:04f9fac5-0d76-4ad5-8211-6a843ba181f8.
- 6906372 author urn:uuid:6cb46cf2-a5f8-4ab9-a758-9875129ecc1f.
- 6906372 author urn:uuid:d901d65a-e6e0-4210-9fe5-3a869249e343.
- 6906372 dateCreated "2015-08-19T10:24:16Z".
- 6906372 dateModified "2024-07-09T11:37:50Z".
- 6906372 name "Interindividual differences in response to treatment with butyrate-producing Butyricicoccus pullicaecorum 25–3T studied in an in vitro gut model".
- 6906372 pagination urn:uuid:d3aa1ffa-0610-4c75-b18e-811d56c5502c.
- 6906372 sameAs LU-6906372.
- 6906372 sourceOrganization urn:uuid:3dae1f9e-724f-49c2-9592-e6112abadcf0.
- 6906372 sourceOrganization urn:uuid:46a7caab-8ae1-4a9b-b9e7-469dc8ae215a.
- 6906372 sourceOrganization urn:uuid:a5c2ec17-3609-421a-8015-635ba20e6199.
- 6906372 type A1.