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- aggregation classification "A1".
- aggregation creator B411153.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2009".
- aggregation format "application/pdf".
- aggregation hasFormat 723771.bibtex.
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- aggregation isPartOf urn:issn:0014-2980.
- aggregation language "eng".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Thymic emigration: Sphingosine-1-phosphate receptor-1-dependent models and beyond".
- aggregation abstract "The thymus is a primary lymphoid organ supporting the development of self-tolerant T cells. Key events in T-cell development in the thymus include lineage commitment, selection events, and thymic emigration. This review discusses the proposed role of sphingosine-1-phosphate and its receptors in the emigration of both conventional and unconventional T-cell subsets from the thymus, and the molecular machinery currently understood to regulate this process. Furthermore, we highlight a role for chemokines and actin-associated proteins in T-cell motility as recent data suggest that T-cell emigration is regulated by more than just a sphingosine-1-phosphate receptor-1-dependent chemotactic axis.".
- aggregation authorList BK728517.
- aggregation endPage "930".
- aggregation issue "4".
- aggregation startPage "925".
- aggregation volume "39".
- aggregation aggregates 740333.
- aggregation isDescribedBy 723771.
- aggregation similarTo eji.200838912.
- aggregation similarTo LU-723771.