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- aggregation classification "C1".
- aggregation creator person.
- aggregation creator person.
- aggregation date "2009".
- aggregation hasFormat 760349.bibtex.
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- aggregation isPartOf urn:isbn:978-3-033-02012-2.
- aggregation language "eng".
- aggregation publisher "University of Bern, Switzerland".
- aggregation rights "I don't know the status of the copyright for this publication".
- aggregation subject "Agriculture and Food Sciences".
- aggregation title "Nutritional improvement of grass pea and cassava to prevent neurolathyrism and konzo".
- aggregation abstract "Grass pea (Lathyrus sativus) is the most drought tolerant legume and a survival food during drought in Ethiopia and the Indian Subcontinent, producing the cheapest dietary protein and saving thousands of lives. It also is a mixed blessing as the cause of an irreversible crippling disease neurolathyrism after prolonged over-consumption. Cassava (Manihot esculenta) is a protein-poor root crop that is the staple food for over half a billion people in Africa, South America and Southeast Asia, where it may be the cheapest source of dietary carbohydrates. Over-consumption of cassava roots in a monotonous diet can cause an irreversible crippling disease konzo, with clinical symptoms indistinguishable from neurolathyrism. The prominent features of both diseases are sudden onset of symmetric spastic paraparesis of the calf muscles and scissor gate. The common feature of grass pea seed and cassava roots is the low content of the essential sulphur containing amino acids methionine and cysteine. The question arises how such different food intake can give rise to such similar symptoms of toxicity and whether the common deficiency in essential amino acids can be the real cause of these crippling diseases. Nevertheless, the focus of breeding has always been the reduction of the neuro-excitatory amino acid beta-ODAP (beta-N-oxalyl-L-alpha,beta-diaminopropionic acid) blamed to be the cause of neurolathyrism in grass pea and the reduction of the cyanogenic glucosinolates in cassava. Developing varieties with higher content in methionine and cysteine may be more relevant in improving nutrition without jeopardizing the tolerance for biotic stress of these crops. An animal model for both diseases does not exist but is essential and urgently needed in order to assess the safety of existing and new varieties.".
- aggregation authorList BK220761.
- aggregation endPage "189".
- aggregation startPage "179".
- aggregation isDescribedBy 760349.
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