Matches in UGent Biblio for { <https://biblio.ugent.be/publication/802424#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B375670.
- aggregation creator B375671.
- aggregation creator B375672.
- aggregation creator B375673.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2009".
- aggregation hasFormat 802424.bibtex.
- aggregation hasFormat 802424.csv.
- aggregation hasFormat 802424.dc.
- aggregation hasFormat 802424.didl.
- aggregation hasFormat 802424.doc.
- aggregation hasFormat 802424.json.
- aggregation hasFormat 802424.mets.
- aggregation hasFormat 802424.mods.
- aggregation hasFormat 802424.rdf.
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- aggregation hasFormat 802424.txt.
- aggregation hasFormat 802424.xls.
- aggregation hasFormat 802424.yaml.
- aggregation isPartOf urn:issn:0173-0835.
- aggregation language "eng".
- aggregation publisher "WILEY-V C H VERLAG GMBH".
- aggregation title "Subcomplexes of mitochondrial complex V reveal mutations in mitochondrial DNA".
- aggregation abstract "Complex V, site of the final step in oxidative phosphorylation, uses the proton gradient across the inner mitochondrial membrane for the production of ATP. It is a multi-subunit complex composed of a catalytic domain (F-1) and a membrane domain (F-0) linked by two stalks. Subcomplexes of complex V containing the F, domain have previously been reported in small series of patients. We report the results in tissue samples and/or cultured skin fibroblasts studied by blue native PAGE followed by activity staining in the gel. Catalytically active subcomplexes of complex V were detected in 66 tissues originating from 53 patients. In 29 of the latter (55%), a mitochondrial DNA (mtDNA) defect was identified. Twelve patients had a pathogenic point mutation in a mitochondrial tRNA, one a large mtDNA deletion, 12 showed mtDNA depletion and four had a mutation in the MT-ATP6 gene. We conclude that the presence of subcomplexes of complex V is a valuable indicator in the detection of mtDNA defects.".
- aggregation authorList BK678369.
- aggregation endPage "3572".
- aggregation issue "20".
- aggregation startPage "3565".
- aggregation volume "30".
- aggregation isDescribedBy 802424.
- aggregation similarTo elps.200900213.
- aggregation similarTo LU-802424.