Matches in Ghent University Academic Bibliography for { <https://biblio.ugent.be/publication/8500765> ?p ?o. }
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- 8500765 classification A1.
- 8500765 date "2016".
- 8500765 language "und".
- 8500765 type journalArticle.
- 8500765 hasPart 8500767.docx.
- 8500765 subject "Chemistry".
- 8500765 doi "10.1039/c6ra08213k".
- 8500765 issn "2046-2069".
- 8500765 issue "59".
- 8500765 volume "6".
- 8500765 abstract "(3R, 4S)-3-Alkoxy/aryloxy-4-(cyanomethyl) azetidin-2-ones were efficiently prepared from readily available 1,2: 5,6-di-D-isopropylidene-D-mannitol by means of a classical organic synthesis approach via 4-hydroxymethyl-beta-lactams as key intermediates. The corresponding 4-carboxymethyl-beta-lactams were subsequently obtained after selective hydrolysis of the nitrile functionality by means of a nitrilase enzyme without affecting the sensitive four-membered ring system, hence overcoming the difficulties associated with the chemical hydrolysis approach. Thus, the implementation of a biocatalytic step allows a convenient synthetic route to new 4-carboxymethyl-beta-lactams as versatile building blocks for further elaboration.".
- 8500765 author 037D1CE6-F0EE-11E1-A9DE-61C894A0A6B4.
- 8500765 author 06C309BA-F0EE-11E1-A9DE-61C894A0A6B4.
- 8500765 author 11145C34-F0EE-11E1-A9DE-61C894A0A6B4.
- 8500765 author 1D0B612C-F0EE-11E1-A9DE-61C894A0A6B4.
- 8500765 author 22304BE0-F0EE-11E1-A9DE-61C894A0A6B4.
- 8500765 author 28170B0C-F0EE-11E1-A9DE-61C894A0A6B4.
- 8500765 author F61853C2-F0ED-11E1-A9DE-61C894A0A6B4.
- 8500765 author F639DE16-F0ED-11E1-A9DE-61C894A0A6B4.
- 8500765 author FAAD4C30-F0ED-11E1-A9DE-61C894A0A6B4.
- 8500765 dateCreated "2017-01-09T11:49:50Z".
- 8500765 dateModified "2024-07-09T12:19:56Z".
- 8500765 name "A nitrilase-mediated entry to 4-carboxymethyl-β-lactams from chemically prepared 4-(cyanomethyl)azetidin-2-ones".
- 8500765 pagination urn:uuid:0a107330-0d3f-4894-9c31-06ede6a0758e.
- 8500765 sameAs LU-8500765.
- 8500765 sourceOrganization urn:uuid:6c5e9c7c-0a51-4bb8-bc25-a07cfbbc0f91.
- 8500765 sourceOrganization urn:uuid:b8ee024f-ba56-4482-b985-da146fb7c2e1.
- 8500765 type A1.