Matches in UGent Biblio for { <https://biblio.ugent.be/publication/852233#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B331811.
- aggregation creator B331812.
- aggregation creator B331813.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2009".
- aggregation hasFormat 852233.bibtex.
- aggregation hasFormat 852233.csv.
- aggregation hasFormat 852233.dc.
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- aggregation hasFormat 852233.doc.
- aggregation hasFormat 852233.json.
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- aggregation isPartOf urn:issn:0936-5214.
- aggregation language "eng".
- aggregation subject "Chemistry".
- aggregation title "Synthesis of 3-aminomethyl-3-fluoropiperidines".
- aggregation abstract "A synthetic route toward new 1-alkyl-3-aminomethyl-3-fluoropiperidines, which are of high interest as building blocks in medicinal chemistry, is described. The Successful approach consists of the fluorination of ethyl 3-chloropropyl-2-cyanoacetate with N-fluorodibenzenesulfonimide (NFSI) and transformation of the ester moiety into different amides, yielding N-alkyl-5-chloro-2-cyano-2-fluoropentanamides. Ring closure was achieved under basic conditions, yielding 1-alkyl-3-fluoro-2-oxopiperidine-3-carbonitriles. After reduction of the obtained lactams with borane, the desired 3-aminomethyl-3-fluoropiperidines were obtained in good yields.".
- aggregation authorList BK626052.
- aggregation endPage "1768".
- aggregation issue "11".
- aggregation startPage "1765".
- aggregation isDescribedBy 852233.
- aggregation similarTo s-0029-1217360.
- aggregation similarTo LU-852233.