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- 8557732 classification A1.
- 8557732 date "2018".
- 8557732 language "eng".
- 8557732 type journalArticle.
- 8557732 hasPart 8557733.pdf.
- 8557732 subject "Medicine and Health Sciences".
- 8557732 doi "10.1017/s000711451800017x".
- 8557732 issn "0007-1145".
- 8557732 issn "1475-2662".
- 8557732 issue "7".
- 8557732 volume "119".
- 8557732 abstract "Balanced vegetarian diets are popular, although they are nearly absent in creatine and carnosine and contain considerably less carnitine than non-vegetarian diets. Few longitudinal intervention studies investigating the effect of a vegetarian diet on the availability of these compounds currently exist. We aimed to investigate the effect of transiently switching omnivores onto a vegetarian diet for 6 months on muscle and plasma creatine, carnitine and carnosine homeostasis. In a 6-month intervention, forty omnivorous women were ascribed to three groups: continued omnivorous diet (control, n 10), vegetarian diet without supplementation (Veg+Pla, n 15) and vegetarian diet combined with daily beta-alanine (0.8\p=n-\0.4 g/d) and creatine supplementation (1 g creatine monohydrate/d) (Veg+Suppl, n 15). Before (0 months; 0M), after 3 months (3M) and 6 months (6M), a fasted venous blood sample and 24-h urine was collected, and muscle carnosine content was determined by proton magnetic resonance spectroscopy (H-1-MRS). Muscle biopsies were obtained at 0M and 3M. Plasma creatine and muscle total creatine content declined from 0M to 3M in Veg+Pla (P=0.013 and P=0.009, respectively), whereas plasma creatine increased from 0M in Veg+Suppl (P=0.004). None of the carnitine-related compounds in plasma or muscle showed a significant time X group interaction effect. H-1-MRS-determined muscle carnosine content was unchanged over 6M in control and Veg+Pla, but increased in Veg+Suppl in soleus (P > 0.001) and gastrocnemius (P=0.001) muscle. To conclude, the body creatine pool declined over a 3-month vegetarian diet in omnivorous women, which was ameliorated when accompanied by low-dose dietary creatine supplementation. Carnitine and carnosine homeostasis was unaffected by a 3- or 6-month vegetarian diet, respectively.".
- 8557732 author 07D58454-F0EE-11E1-A9DE-61C894A0A6B4.
- 8557732 author 088CC63C-F0EE-11E1-A9DE-61C894A0A6B4.
- 8557732 author F41E7EB6-F0ED-11E1-A9DE-61C894A0A6B4.
- 8557732 author F47B132E-F0ED-11E1-A9DE-61C894A0A6B4.
- 8557732 author F4A465E4-F0ED-11E1-A9DE-61C894A0A6B4.
- 8557732 author F4EB187C-F0ED-11E1-A9DE-61C894A0A6B4.
- 8557732 author F4EF24F8-F0ED-11E1-A9DE-61C894A0A6B4.
- 8557732 author F7148516-F0ED-11E1-A9DE-61C894A0A6B4.
- 8557732 author F9665006-F0ED-11E1-A9DE-61C894A0A6B4.
- 8557732 author FB7033E4-F0ED-11E1-A9DE-61C894A0A6B4.
- 8557732 author urn:uuid:1e8fffff-2d3f-426e-93db-fd9440d43494.
- 8557732 author urn:uuid:35472045-6dad-4d14-b9ed-0ad1f0f10b87.
- 8557732 dateCreated "2018-03-28T16:48:14Z".
- 8557732 dateModified "2024-11-27T18:56:08Z".
- 8557732 name "Changing to a vegetarian diet reduces the body creatine pool in omnivorous women, but appears not to affect carnitine and carnosine homeostasis : a randomised trial".
- 8557732 pagination urn:uuid:086ffbcc-90a4-4bf4-9bf6-ac5549d9bb95.
- 8557732 sameAs LU-8557732.
- 8557732 sourceOrganization urn:uuid:03e5eed1-59f0-461f-8abd-1860677e3567.
- 8557732 sourceOrganization urn:uuid:5208f91d-2fa4-4551-9793-afdc5810f764.
- 8557732 sourceOrganization urn:uuid:9b1e35da-a6d4-4b9b-8078-ff342898ed85.
- 8557732 sourceOrganization urn:uuid:d0597fc4-9d21-4652-bd0a-24cc166650cb.
- 8557732 sourceOrganization urn:uuid:f80d7887-9e74-4bd2-89c8-48f5f6ea63af.
- 8557732 type A1.