Matches in UGent Biblio for { <https://biblio.ugent.be/publication/880930#aggregation> ?p ?o. }
Showing items 1 to 35 of
35
with 100 items per page.
- aggregation classification "A1".
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation creator person.
- aggregation date "2009".
- aggregation hasFormat 880930.bibtex.
- aggregation hasFormat 880930.csv.
- aggregation hasFormat 880930.dc.
- aggregation hasFormat 880930.didl.
- aggregation hasFormat 880930.doc.
- aggregation hasFormat 880930.json.
- aggregation hasFormat 880930.mets.
- aggregation hasFormat 880930.mods.
- aggregation hasFormat 880930.rdf.
- aggregation hasFormat 880930.ris.
- aggregation hasFormat 880930.txt.
- aggregation hasFormat 880930.xls.
- aggregation hasFormat 880930.yaml.
- aggregation isPartOf urn:issn:0001-5458.
- aggregation language "eng".
- aggregation publisher "ACTA MEDICAL BELGICA".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Defining the Optimal Therapy Sequence in Synchronous Resectable Liver Metastases from Colorectal Cancer: A Decision Analysis Approach".
- aggregation abstract "Introduction : Approximately 5%-20% of colorectal cancer (CRC) patients present with synchronous potentially resectable liver metastatic disease. Preclinical and clinical studies suggest a benefit of the 'liver first' approach, i.e. resection of the liver metastasis followed by resection of the primary tumour. A formal decision analysis may support a rational choice between several therapy options. Methods : Survival and morbidity data were retrieved from relevant clinical studies identified by a Web of Science (R) search. Data were entered into decision analysis software (TreeAge (R) Pro 2009, Williamstown, MA, USA). Transition probabilities including the risk of death from complications or disease progression associated with individual therapy options were entered into the model. Sensitivity analysis was performed to evaluate the model's validity under a variety of assumptions. Results : The result of the decision analysis confirms the superiority of the 'liver first' approach. Sensitivity analysis demonstrated that this assumption is valid on condition that the mortality associated with the hepatectomy first is <4.5%, and that the mortality of colectomy performed after hepatectomy is <3.2%. Conclusion : The results of this decision analysis suggest that, in patients with synchronous resectable colorectal liver metastases, the 'liver first' approach is to be preferred. Randomized trials will be needed to confirm the results of this. simulation based outcome.".
- aggregation authorList BK959889.
- aggregation endPage "320".
- aggregation issue "3".
- aggregation startPage "317".
- aggregation volume "109".
- aggregation isDescribedBy 880930.
- aggregation similarTo LU-880930.