Matches in UGent Biblio for { <https://biblio.ugent.be/publication/898306#aggregation> ?p ?o. }
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- aggregation classification "A1".
- aggregation creator B378614.
- aggregation creator B378615.
- aggregation creator B378616.
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- aggregation date "2010".
- aggregation format "application/pdf".
- aggregation hasFormat 898306.bibtex.
- aggregation hasFormat 898306.csv.
- aggregation hasFormat 898306.dc.
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- aggregation hasFormat 898306.yaml.
- aggregation isPartOf urn:issn:0194-911X.
- aggregation language "eng".
- aggregation rights "I have transferred the copyright for this publication to the publisher".
- aggregation subject "Medicine and Health Sciences".
- aggregation title "Left ventricular mass: allometric scaling, normative values, effect of obesity, and prognostic performance".
- aggregation abstract "The need for left ventricular mass (LVM) normalization to body size is well recognized. Currently used allometric exponents to normalize LVM may not account for the confounding effect of sex. Because sex is a strong determinant of body size and LVM, we hypothesized that these are subject to potential bias. We analyzed data from 7528 subjects enrolled in the Asklepios Study (n = 2524) and the Multiethnic Study of Atherosclerosis (limited access data set; n = 5,004) to assess metric relationships between LVM and body size, generate normative data for indexed LVM, and compare the ability of normalization methods to predict cardiovascular events. The allometric exponent that adequately described the LVM-body height relationship was 1.7 in both studies and significantly different from both the unity and 2.7, whereas the LVM-body surface area relationship was approximately linear. LVM/height(2.7) consistently demonstrated important residual relationships with body height and systematically misclassified subjects regarding the presence of LVH. LVH defined by LVM/height(1.7) was more sensitive than LVM/body surface area to identify obesity-related LVH and was most consistently associated with cardiovascular events and all-cause death. In contrast to current assumptions, LVM/height(2.7) is not an adequate method to normalize LVM for body size. We provide more appropriate normalization methods, normative data by 2D echocardiography and gradient-echo cardiac MRI, and cutoffs for defining LVH, along with prognostic validation data.".
- aggregation authorList BK683953.
- aggregation endPage "98".
- aggregation issue "1".
- aggregation startPage "91".
- aggregation volume "56".
- aggregation aggregates 1092493.
- aggregation aggregates 952086.
- aggregation isDescribedBy 898306.
- aggregation similarTo HYPERTENSIONAHA.110.150250.
- aggregation similarTo LU-898306.