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- 5-HT2C_receptor_agonists abstract "Serotonin 5-HT2 receptors are stimulated by monoaminergic neurotransmitters including serotonin, dopamine and norepinephrine. 5-HT2 receptor stimulation causes a buildup of intracellular inositol triphosphate and thereby an increase of cytosolic Ca2+. 5-HT2C receptor agonists are attractive drug targets that have potential use in the treatment of a number of conditions including obesity, psychiatric disorders, sexual dysfunction and urinary incontinence.The 5-HT2C receptors are one of three subtypes that belong to the serotonin 5-HT2 receptor subfamily along with 5-HT2A and 5-HT2B receptors. The development of 5-HT2C agonists have been a major obstacle, because of severe side effects due to a lack of selectivity over 5-HT2A and 5-HT2B receptors. Activation of 5-HT2A receptors can induce hallucinations, and the activation of 5-HT2B receptors has been implicated in cardiac valvular insufficiency and possibly in pulmonary hypertension.".
- 5-HT2C_receptor_agonists thumbnail Fenfluramine.png?width=300.
- 5-HT2C_receptor_agonists wikiPageID "37127342".
- 5-HT2C_receptor_agonists wikiPageRevisionID "604983763".
- 5-HT2C_receptor_agonists align "center".
- 5-HT2C_receptor_agonists alt "Derivative 1".
- 5-HT2C_receptor_agonists alt "Derivative 2".
- 5-HT2C_receptor_agonists alt "Derivative 3".
- 5-HT2C_receptor_agonists alt "Derivative 4".
- 5-HT2C_receptor_agonists alt "Derivative 5".
- 5-HT2C_receptor_agonists alt "Pyrazolo[3,4-d]pyrimidine core".
- 5-HT2C_receptor_agonists caption "A potent mCPP derivative".
- 5-HT2C_receptor_agonists caption "Derivative 1".
- 5-HT2C_receptor_agonists caption "Derivative 2".
- 5-HT2C_receptor_agonists caption "Derivative 3".
- 5-HT2C_receptor_agonists caption "Derivative 4".
- 5-HT2C_receptor_agonists caption "Derivative 5".
- 5-HT2C_receptor_agonists caption "Pyrazolo[3,4-d]pyrimidine core".
- 5-HT2C_receptor_agonists caption "mCPP".
- 5-HT2C_receptor_agonists footer "Figure 6. Pyrazolo[3,4-d]pyrimidine derivatives.".
- 5-HT2C_receptor_agonists footer "Figure 8. mCPP and a potent derivative.".
- 5-HT2C_receptor_agonists hasPhotoCollection 5-HT2C_receptor_agonists.
- 5-HT2C_receptor_agonists image "MCCP.jpg".
- 5-HT2C_receptor_agonists image "MCPP derivative.jpg".
- 5-HT2C_receptor_agonists image "Pyrazolo 3,4-d pyrimidine core.png".
- 5-HT2C_receptor_agonists image "Pyrazolo 3,4-d pyrimidine derivative 1.png".
- 5-HT2C_receptor_agonists image "Pyrazolo 3,4-d pyrimidine derivative 2.png".
- 5-HT2C_receptor_agonists image "Pyrazolo 3,4-d pyrimidine derivative 3.png".
- 5-HT2C_receptor_agonists image "Pyrazolo 3,4-d pyrimidine derivative 4.png".
- 5-HT2C_receptor_agonists image "Pyrazolo 3,4-d pyrimidine derivative 5.png".
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- 5-HT2C_receptor_agonists width "150".
- 5-HT2C_receptor_agonists width "200".
- 5-HT2C_receptor_agonists subject Category:Antiobesity_drugs.
- 5-HT2C_receptor_agonists subject Category:Drug_discovery.
- 5-HT2C_receptor_agonists subject Category:Serotonin_receptor_agonists.
- 5-HT2C_receptor_agonists comment "Serotonin 5-HT2 receptors are stimulated by monoaminergic neurotransmitters including serotonin, dopamine and norepinephrine. 5-HT2 receptor stimulation causes a buildup of intracellular inositol triphosphate and thereby an increase of cytosolic Ca2+.".
- 5-HT2C_receptor_agonists label "5-HT2C receptor agonists".
- 5-HT2C_receptor_agonists sameAs m.0n3xqrz.
- 5-HT2C_receptor_agonists sameAs Q4639597.
- 5-HT2C_receptor_agonists sameAs Q4639597.
- 5-HT2C_receptor_agonists wasDerivedFrom 5-HT2C_receptor_agonists?oldid=604983763.
- 5-HT2C_receptor_agonists depiction Fenfluramine.png.
- 5-HT2C_receptor_agonists isPrimaryTopicOf 5-HT2C_receptor_agonists.
