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- ACT_Biotech_Inc abstract "ACT Biotech Inc is a San Francisco-based, privately held biopharmaceutical company focused on the development and commercialization of targeted cancer drugs.The Company's clinical stage pipeline includes :Telatinib, an oral kinase inhibitor for the first-line treatment of advanced gastric cancer. It has been granted Orphan Drug status by the U.S. Food and Drug Administration (FDA). It has reported encouraging interim results from a phase II trial.ACTB1003, an oral kinase inhibitor that targets cancer cells through multiple modes of action. It inhibits cancer cell growth by targeting the FGF receptor family, which are mutated in a number of human cancer types. ACTB1003 also directly induces apoptosis by targeting kinases downstream of the PI3K pathway, all at low nanomolar concentrations.Other pipeline products include an oral Aurora A and B kinase inhibitor at the pre-IND stage, and an ABL tyrosine kinase inhibitor targeting the T315I mutant enzyme in pre-clinical development.".
- ACT_Biotech_Inc wikiPageExternalLink www.actbiotech.com.
- ACT_Biotech_Inc wikiPageID "29254986".
- ACT_Biotech_Inc wikiPageRevisionID "506298053".
- ACT_Biotech_Inc hasPhotoCollection ACT_Biotech_Inc.
- ACT_Biotech_Inc subject Category:Biotechnology_companies_of_the_United_States.
- ACT_Biotech_Inc subject Category:Pharmaceutical_companies_of_the_United_States.
- ACT_Biotech_Inc type Abstraction100002137.
- ACT_Biotech_Inc type BiotechnologyCompanies.
- ACT_Biotech_Inc type Company108058098.
- ACT_Biotech_Inc type DrugCompany108002578.
- ACT_Biotech_Inc type Group100031264.
- ACT_Biotech_Inc type Institution108053576.
- ACT_Biotech_Inc type Organization108008335.
- ACT_Biotech_Inc type PharmaceuticalCompaniesOfTheUnitedStates.
- ACT_Biotech_Inc type SocialGroup107950920.
- ACT_Biotech_Inc type YagoLegalActor.
- ACT_Biotech_Inc type YagoLegalActorGeo.
- ACT_Biotech_Inc type YagoPermanentlyLocatedEntity.
- ACT_Biotech_Inc comment "ACT Biotech Inc is a San Francisco-based, privately held biopharmaceutical company focused on the development and commercialization of targeted cancer drugs.The Company's clinical stage pipeline includes :Telatinib, an oral kinase inhibitor for the first-line treatment of advanced gastric cancer. It has been granted Orphan Drug status by the U.S. Food and Drug Administration (FDA).".
- ACT_Biotech_Inc label "ACT Biotech Inc".
- ACT_Biotech_Inc sameAs m.0dln6n3.
- ACT_Biotech_Inc sameAs Q4650874.
- ACT_Biotech_Inc sameAs Q4650874.
- ACT_Biotech_Inc sameAs ACT_Biotech_Inc.
- ACT_Biotech_Inc wasDerivedFrom ACT_Biotech_Inc?oldid=506298053.
- ACT_Biotech_Inc isPrimaryTopicOf ACT_Biotech_Inc.