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- ACT_domain abstract "In molecular biology, the ACT domain is a protein domain that is found in a variety of proteins involved in metabolism. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. The ACT domain is named after three of the proteins that contain it: aspartate kinase, chorismate mutase and TyrA. The archetypical ACT domain is the C-terminal regulatory domain of 3-phosphoglycerate dehydrogenase (3PGDH), which folds with a ferredoxin-like topology. A pair of ACT domains form an eight-stranded antiparallel sheet with two molecules of allosteric inhibitor serine bound in the interface. Biochemical exploration of a few other proteins containing ACT domains supports the suggestions that these domains contain the archetypical ACT structure.The ACT domain was discovered by Aravind and Koonin using iterative sequence searches.".
- ACT_domain symbol "ACT".
- ACT_domain thumbnail PDB_2j0w_EBI.jpg?width=300.
- ACT_domain wikiPageID "32019370".
- ACT_domain wikiPageRevisionID "590285625".
- ACT_domain caption "Crystal structure of E. coli aspartokinase iii in complex with aspartate and adp".
- ACT_domain cdd "cd02116".
- ACT_domain hasPhotoCollection ACT_domain.
- ACT_domain interpro "IPR002912".
- ACT_domain name "ACT".
- ACT_domain pfam "PF01842".
- ACT_domain pfamClan "CL0070".
- ACT_domain scop "1".
- ACT_domain symbol "ACT".
- ACT_domain subject Category:Protein_domains.
- ACT_domain type Abstraction100002137.
- ACT_domain type Attribute100024264.
- ACT_domain type Environment113934596.
- ACT_domain type ProteinDomains.
- ACT_domain type Situation113927383.
- ACT_domain type Sphere114514039.
- ACT_domain type State100024720.
- ACT_domain type Biomolecule.
- ACT_domain type Protein.
- ACT_domain type BiologicalObject.
- ACT_domain comment "In molecular biology, the ACT domain is a protein domain that is found in a variety of proteins involved in metabolism. ACT domains are linked to a wide range of metabolic enzymes that are regulated by amino acid concentration. The ACT domain is named after three of the proteins that contain it: aspartate kinase, chorismate mutase and TyrA. The archetypical ACT domain is the C-terminal regulatory domain of 3-phosphoglycerate dehydrogenase (3PGDH), which folds with a ferredoxin-like topology.".
- ACT_domain label "ACT domain".
- ACT_domain sameAs m.0gx0rh5.
- ACT_domain sameAs Q4650899.
- ACT_domain sameAs Q4650899.
- ACT_domain sameAs ACT_domain.
- ACT_domain wasDerivedFrom ACT_domain?oldid=590285625.
- ACT_domain depiction PDB_2j0w_EBI.jpg.
- ACT_domain isPrimaryTopicOf ACT_domain.
