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- ADARB1 abstract "Double-stranded RNA-specific editase 1 is an enzyme that in humans is encoded by the ADARB1 gene.This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.ADAR2 requires the small molecule inositol hexakisphosphate (IP6) for proper function.".
- ADARB1 entrezgene "104".
- ADARB1 wikiPageID "14762572".
- ADARB1 wikiPageRevisionID "603828452".
- ADARB1 hasPhotoCollection ADARB1.
- ADARB1 requireManualInspection "no".
- ADARB1 summaryText "This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.".
- ADARB1 updateCitations "yes".
- ADARB1 updatePage "yes".
- ADARB1 updateProteinBox "yes".
- ADARB1 updateSummary "yes".
- ADARB1 subject Category:EC_3.5.
- ADARB1 type Biomolecule.
- ADARB1 type Protein.
- ADARB1 type BiologicalObject.
- ADARB1 comment "Double-stranded RNA-specific editase 1 is an enzyme that in humans is encoded by the ADARB1 gene.This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site.".
- ADARB1 label "ADARB1".
- ADARB1 sameAs m.03gx3tk.
- ADARB1 sameAs Q4651019.
- ADARB1 sameAs Q4651019.
- ADARB1 wasDerivedFrom ADARB1?oldid=603828452.
- ADARB1 isPrimaryTopicOf ADARB1.