Matches in DBpedia 2014 for { <http://dbpedia.org/resource/AKR1C3> ?p ?o. }
Showing items 1 to 24 of
24
with 100 items per page.
- AKR1C3 abstract "Aldo-keto reductase family 1 member C3 is a key steroidogenic enzyme that in humans is encoded by the AKR1C3 gene.This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.".
- AKR1C3 entrezgene "8644".
- AKR1C3 wikiPageID "14754280".
- AKR1C3 wikiPageRevisionID "597514063".
- AKR1C3 hasPhotoCollection AKR1C3.
- AKR1C3 requireManualInspection "no".
- AKR1C3 summaryText "This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin D2, PGH2 and phenanthrenequinone , and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.".
- AKR1C3 updateCitations "yes".
- AKR1C3 updatePage "yes".
- AKR1C3 updateProteinBox "yes".
- AKR1C3 updateSummary "yes".
- AKR1C3 subject Category:EC_1.1.
- AKR1C3 type Biomolecule.
- AKR1C3 type Protein.
- AKR1C3 type BiologicalObject.
- AKR1C3 comment "Aldo-keto reductase family 1 member C3 is a key steroidogenic enzyme that in humans is encoded by the AKR1C3 gene.This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity.".
- AKR1C3 label "AKR1C3".
- AKR1C3 label "AKR1C3".
- AKR1C3 sameAs m.03gwqpy.
- AKR1C3 sameAs Q4652190.
- AKR1C3 sameAs Q4652190.
- AKR1C3 sameAs 650.
- AKR1C3 wasDerivedFrom AKR1C3?oldid=597514063.
- AKR1C3 isPrimaryTopicOf AKR1C3.