Matches in DBpedia 2014 for { <http://dbpedia.org/resource/ANTXR1> ?p ?o. }
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- ANTXR1 abstract "Anthrax toxin receptor 1 is a protein that in humans is encoded by the ANTXR1 gene.The protein encoded by this gene is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants have been described.".
- ANTXR1 entrezgene "84168".
- ANTXR1 wikiPageID "14770156".
- ANTXR1 wikiPageRevisionID "590597585".
- ANTXR1 hasPhotoCollection ANTXR1.
- ANTXR1 requireManualInspection "no".
- ANTXR1 summaryText "The protein encoded by this gene is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor and lethal factor disrupt normal cellular processes. Three alternatively spliced variants have been described.".
- ANTXR1 updateCitations "yes".
- ANTXR1 updatePage "yes".
- ANTXR1 updateProteinBox "yes".
- ANTXR1 updateSummary "yes".
- ANTXR1 type Biomolecule.
- ANTXR1 type Protein.
- ANTXR1 type BiologicalObject.
- ANTXR1 comment "Anthrax toxin receptor 1 is a protein that in humans is encoded by the ANTXR1 gene.The protein encoded by this gene is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax.".
- ANTXR1 label "ANTXR1".
- ANTXR1 sameAs m.03gxdfp.
- ANTXR1 sameAs Q4653068.
- ANTXR1 sameAs Q4653068.
- ANTXR1 wasDerivedFrom ANTXR1?oldid=590597585.
- ANTXR1 isPrimaryTopicOf ANTXR1.