Matches in DBpedia 2014 for { <http://dbpedia.org/resource/APOBEC1> ?p ?o. }
Showing items 1 to 18 of
18
with 100 items per page.
- APOBEC1 abstract "C->U-editing enzyme APOBEC-1 also known as apolipoprotein B mRNA-editing enzyme 1 is a protein that in humans is encoded by the APOBEC1 gene.This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromin 1 mRNAs.APOBEC-1 (A1) is an enzyme in the cytidine deaminase family that has been linked with cholesterol control, cancer development and inhibition of viral replication. Its function relies on introducing a stop codon into apolipoprotein B (ApoB) mRNA, which alters lipid metabolism in the gastrointestinal tract. The editing mechanism is highly specific, working in conjunction with A1 complementation factor (ACF). A1’s deamination of the cytosine base yields uracil, which calls for the stop codon in the protein.A1 has been linked with both positive and negative health effects. In rodents, it has wide tissue distribution where as in humans, it is only expressed in the small intestine.".
- APOBEC1 entrezgene "339".
- APOBEC1 thumbnail Deamination_of_cytidine.png?width=300.
- APOBEC1 wikiPageID "14761730".
- APOBEC1 wikiPageRevisionID "606657031".
- APOBEC1 hasPhotoCollection APOBEC1.
- APOBEC1 subject Category:EC_3.5.4.
- APOBEC1 type Biomolecule.
- APOBEC1 type Protein.
- APOBEC1 type BiologicalObject.
- APOBEC1 comment "C->U-editing enzyme APOBEC-1 also known as apolipoprotein B mRNA-editing enzyme 1 is a protein that in humans is encoded by the APOBEC1 gene.This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP).".
- APOBEC1 label "APOBEC1".
- APOBEC1 sameAs m.03gx2cd.
- APOBEC1 sameAs Q4653352.
- APOBEC1 sameAs Q4653352.
- APOBEC1 wasDerivedFrom APOBEC1?oldid=606657031.
- APOBEC1 depiction Deamination_of_cytidine.png.
- APOBEC1 isPrimaryTopicOf APOBEC1.
