Matches in DBpedia 2014 for { <http://dbpedia.org/resource/APPBP1> ?p ?o. }
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- APPBP1 abstract "NEDD8-activating enzyme E1 regulatory subunit is a protein that in humans is encoded by the NAE1 gene.The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.".
- APPBP1 entrezgene "8883".
- APPBP1 wikiPageID "14798064".
- APPBP1 wikiPageRevisionID "603295347".
- APPBP1 hasPhotoCollection APPBP1.
- APPBP1 requireManualInspection "no".
- APPBP1 summaryText "The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.".
- APPBP1 updateCitations "yes".
- APPBP1 updatePage "yes".
- APPBP1 updateProteinBox "yes".
- APPBP1 updateSummary "yes".
- APPBP1 type Biomolecule.
- APPBP1 type Protein.
- APPBP1 type BiologicalObject.
- APPBP1 comment "NEDD8-activating enzyme E1 regulatory subunit is a protein that in humans is encoded by the NAE1 gene.The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein.".
- APPBP1 label "APPBP1".
- APPBP1 sameAs m.03gyb0w.
- APPBP1 sameAs Q15996557.
- APPBP1 sameAs Q15996557.
- APPBP1 sameAs 225.
- APPBP1 wasDerivedFrom APPBP1?oldid=603295347.
- APPBP1 isPrimaryTopicOf APPBP1.