Matches in DBpedia 2014 for { <http://dbpedia.org/resource/ASK1> ?p ?o. }
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- ASK1 abstract "Apoptosis signal-regulating kinase 1 (ASK1) also known as mitogen-activated protein kinase kinase kinase 5 (MAP3K5) is a member of MAP kinase kinase kinase family and as such a part of mitogen-activated protein kinase pathway. It activates c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinases in a Raf-independent fashion in response to an array of stresses such as oxidative stress, endoplasmic reticulum stress and calcium influx. ASK1 has been found to be involved in cancer, diabetes, cardiovascular and neurodegenerative diseases.MAP3K5 gene coding for the protein is located on chromosome 6 at locus 6q22.33. and the transcribed protein contains 1,374 amino acids with 11 kinase subdomains.[citation needed] Northern blot analysis shows that MAP3K5 transcript is abundant in human heart and pancreas.".
- ASK1 entrezgene "4217".
- ASK1 wikiPageID "11628066".
- ASK1 wikiPageRevisionID "602081393".
- ASK1 hasPhotoCollection ASK1.
- ASK1 subject Category:Apoptosis.
- ASK1 subject Category:EC_2.7.11.
- ASK1 subject Category:Programmed_cell_death.
- ASK1 type Biomolecule.
- ASK1 type Protein.
- ASK1 type BiologicalObject.
- ASK1 comment "Apoptosis signal-regulating kinase 1 (ASK1) also known as mitogen-activated protein kinase kinase kinase 5 (MAP3K5) is a member of MAP kinase kinase kinase family and as such a part of mitogen-activated protein kinase pathway. It activates c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein kinases in a Raf-independent fashion in response to an array of stresses such as oxidative stress, endoplasmic reticulum stress and calcium influx.".
- ASK1 label "ASK1".
- ASK1 sameAs m.02w0md7.
- ASK1 sameAs Q4654263.
- ASK1 sameAs Q4654263.
- ASK1 wasDerivedFrom ASK1?oldid=602081393.
- ASK1 isPrimaryTopicOf ASK1.