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- ATP1B1 abstract "Sodium/potassium-transporting ATPase subunit beta-1 is an enzyme that in humans is encoded by the ATP1B1 gene.The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+-ATPases. Na+/K+-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+-ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.".
- ATP1B1 entrezgene "481".
- ATP1B1 wikiPageID "14764523".
- ATP1B1 wikiPageRevisionID "574846078".
- ATP1B1 hasPhotoCollection ATP1B1.
- ATP1B1 requireManualInspection "no".
- ATP1B1 summaryText "The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+-ATPases. Na+/K+-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit and a smaller glycoprotein subunit . The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+-ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been identified.".
- ATP1B1 updateCitations "yes".
- ATP1B1 updatePage "yes".
- ATP1B1 updateProteinBox "yes".
- ATP1B1 updateSummary "yes".
- ATP1B1 type Biomolecule.
- ATP1B1 type Protein.
- ATP1B1 type BiologicalObject.
- ATP1B1 comment "Sodium/potassium-transporting ATPase subunit beta-1 is an enzyme that in humans is encoded by the ATP1B1 gene.The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+-ATPases. Na+/K+-ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane.".
- ATP1B1 label "ATP1B1".
- ATP1B1 sameAs m.03gx6wk.
- ATP1B1 sameAs Q4654802.
- ATP1B1 sameAs Q4654802.
- ATP1B1 wasDerivedFrom ATP1B1?oldid=574846078.
- ATP1B1 isPrimaryTopicOf ATP1B1.