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- ATP1B3 abstract "Sodium/potassium-transporting ATPase subunit beta-3 is an enzyme that in humans is encoded by the ATP1B3 gene. ATP1B3 has also been designated as CD298 (cluster of differentiation 298).The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.".
- ATP1B3 entrezgene "483".
- ATP1B3 wikiPageID "15062801".
- ATP1B3 wikiPageRevisionID "590713787".
- ATP1B3 hasPhotoCollection ATP1B3.
- ATP1B3 requireManualInspection "no".
- ATP1B3 summaryText "The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit and a smaller glycoprotein subunit . The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2.".
- ATP1B3 updateCitations "yes".
- ATP1B3 updatePage "yes".
- ATP1B3 updateProteinBox "yes".
- ATP1B3 updateSummary "yes".
- ATP1B3 subject Category:Clusters_of_differentiation.
- ATP1B3 type Biomolecule.
- ATP1B3 type Protein.
- ATP1B3 type BiologicalObject.
- ATP1B3 comment "Sodium/potassium-transporting ATPase subunit beta-3 is an enzyme that in humans is encoded by the ATP1B3 gene. ATP1B3 has also been designated as CD298 (cluster of differentiation 298).The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane.".
- ATP1B3 label "ATP1B3".
- ATP1B3 sameAs m.03hg6r9.
- ATP1B3 sameAs Q4654803.
- ATP1B3 sameAs Q4654803.
- ATP1B3 wasDerivedFrom ATP1B3?oldid=590713787.
- ATP1B3 isPrimaryTopicOf ATP1B3.