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- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 abstract "V-type proton ATPase 116 kDa subunit a isoform 1 is an enzyme that in humans is encoded by the ATP6V0A1 gene.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. The occurrence of splice variants encoding different protein products has been reported, but the full-length natures of these transcripts have not been determined.".
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 entrezgene "535".
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 wikiPageID "14797164".
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 wikiPageRevisionID "590714741".
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 hasPhotoCollection ATPase,_H+_transporting,_lysosomal_V0_subunit_a1.
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 requireManualInspection "no".
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 summaryText "This gene encodes a component of vacuolar ATPase , a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c", and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. The occurrence of splice variants encoding different protein products has been reported, but the full-length natures of these transcripts have not been determined.".
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 updateCitations "yes".
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 updatePage "yes".
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 updateProteinBox "yes".
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 updateSummary "yes".
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 type Biomolecule.
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 type Protein.
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 type BiologicalObject.
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 comment "V-type proton ATPase 116 kDa subunit a isoform 1 is an enzyme that in humans is encoded by the ATP6V0A1 gene.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation.".
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 label "ATPase, H+ transporting, lysosomal V0 subunit a1".
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 sameAs m.03gy8hd.
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 sameAs Q4654892.
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 sameAs Q4654892.
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 wasDerivedFrom ATPase,_H+_transporting,_lysosomal_V0_subunit_a1?oldid=590714741.
- ATPase,_H+_transporting,_lysosomal_V0_subunit_a1 isPrimaryTopicOf ATPase,_H+_transporting,_lysosomal_V0_subunit_a1.