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- Action_potential abstract "In physiology, an action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and endocrine cells, as well as in some plant cells. In neurons, they play a central role in cell-to-cell communication. In other types of cells, their main function is to activate intracellular processes. In muscle cells, for example, an action potential is the first step in the chain of events leading to contraction. In beta cells of the pancreas, they provoke release of insulin. Action potentials in neurons are also known as "nerve impulses" or "spikes", and the temporal sequence of action potentials generated by a neuron is called its "spike train". A neuron that emits an action potential is often said to "fire".Action potentials are generated by special types of voltage-gated ion channels embedded in a cell's plasma membrane. These channels are shut when the membrane potential is near the resting potential of the cell, but they rapidly begin to open if the membrane potential increases to a precisely defined threshold value. When the channels open (by detecting the depolarization in transmembrane voltage), they allow an inward flow of sodium ions, which changes the electrochemical gradient, which in turn produces a further rise in the membrane potential. This then causes more channels to open, producing a greater electric current across the cell membrane, and so on. The process proceeds explosively until all of the available ion channels are open, resulting in a large upswing in the membrane potential. The rapid influx of sodium ions causes the polarity of the plasma membrane to reverse, and the ion channels then rapidly inactivate. As the sodium channels close, sodium ions can no longer enter the neuron, and they are actively transported out of the plasma membrane. Potassium channels are then activated, and there is an outward current of potassium ions, returning the electrochemical gradient to the resting state. After an action potential has occurred, there is a transient negative shift, called the afterhyperpolarization or refractory period, due to additional potassium currents. This is the mechanism that prevents an action potential from traveling back the way it just came.In animal cells, there are two primary types of action potentials, one type generated by voltage-gated sodium channels, the other by voltage-gated calcium channels. Sodium-based action potentials usually last for under one millisecond, whereas calcium-based action potentials may last for 100 milliseconds or longer. In some types of neurons, slow calcium spikes provide the driving force for a long burst of rapidly emitted sodium spikes. In cardiac muscle cells, on the other hand, an initial fast sodium spike provides a "primer" to provoke the rapid onset of a calcium spike, which then produces muscle contraction.".
- Action_potential thumbnail Action_Potential.gif?width=300.
- Action_potential wikiPageExternalLink 4402001.html.
- Action_potential wikiPageExternalLink cese.sourceforge.net.
- Action_potential wikiPageExternalLink chapter01.html.
- Action_potential wikiPageExternalLink ~hvg2s.
- Action_potential wikiPageExternalLink CAPindex.html.
- Action_potential wikiPageExternalLink apneuron.html.
- Action_potential wikiPageExternalLink index.html.
- Action_potential wikiPageExternalLink actionp.html.
- Action_potential wikiPageExternalLink channel.html.
- Action_potential wikiPageExternalLink action_potential_cartoon.swf.
- Action_potential wikiPageExternalLink bv.fcgi?rid=neurosci.section.326.
- Action_potential wikiPageExternalLink www.nernstgoldman.physiology.arizona.edu.
- Action_potential wikiPageExternalLink electrotonic-action%20potential.
- Action_potential wikiPageID "156998".
- Action_potential wikiPageRevisionID "605992039".
- Action_potential hasPhotoCollection Action_potential.
- Action_potential subject Category:Cellular_neuroscience.
- Action_potential subject Category:Cellular_processes.
- Action_potential subject Category:Computational_neuroscience.
- Action_potential subject Category:Electrochemistry.
- Action_potential subject Category:Electrophysiology.
- Action_potential subject Category:Membrane_biology.
- Action_potential subject Category:Nervous_system.
- Action_potential subject Category:Neural_coding.
- Action_potential comment "In physiology, an action potential is a short-lasting event in which the electrical membrane potential of a cell rapidly rises and falls, following a consistent trajectory. Action potentials occur in several types of animal cells, called excitable cells, which include neurons, muscle cells, and endocrine cells, as well as in some plant cells. In neurons, they play a central role in cell-to-cell communication. In other types of cells, their main function is to activate intracellular processes.".
- Action_potential label "Actiepotentiaal".
- Action_potential label "Action potential".
- Action_potential label "Aktionspotential".
- Action_potential label "Potencial de acción".
- Action_potential label "Potencial de ação".
- Action_potential label "Potencjał czynnościowy".
- Action_potential label "Potentiel d'action".
- Action_potential label "Potenziale d'azione".
- Action_potential label "Потенциал действия".
- Action_potential label "جهد الفعل".
- Action_potential label "动作电位".
- Action_potential label "活動電位".
- Action_potential sameAs Akční_potenciál.
- Action_potential sameAs Aktionspotential.
- Action_potential sameAs Δυναμικό_ενέργειας.
- Action_potential sameAs Potencial_de_acción.
- Action_potential sameAs Ekintza_potentzial.
- Action_potential sameAs Potentiel_d'action.
- Action_potential sameAs Potensial_aksi.
- Action_potential sameAs Potenziale_d'azione.
- Action_potential sameAs 活動電位.
- Action_potential sameAs 활동전위.
- Action_potential sameAs Actiepotentiaal.
- Action_potential sameAs Potencjał_czynnościowy.
- Action_potential sameAs Potencial_de_ação.
- Action_potential sameAs m.014mmx.
- Action_potential sameAs Q194277.
- Action_potential sameAs Q194277.
- Action_potential wasDerivedFrom Action_potential?oldid=605992039.
- Action_potential depiction Action_Potential.gif.
- Action_potential isPrimaryTopicOf Action_potential.