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- Adaptive_immune_system abstract "The adaptive immune system, also known as the acquired immune system or, more rarely, as the specific immune system, is a subsystem of the overall immune system that is composed of highly specialized, systemic cells and processes that eliminate or prevent pathogen growth. One of the two main immunity strategies found in vertebrates (the other being the innate immune system), acquired immunity creates immunological memory after an initial response to a specific pathogen, leading to an enhanced response to subsequent encounters with that same pathogen. This process of acquired immunity is the basis of vaccination. Like the innate system, the adaptive system includes both humoral immunity components and cell-mediated immunity components.In acquired immunity, pathogen-specific receptors are "acquired" during the lifetime of the organism (whereas in innate immunity pathogen-specific receptors are already encoded in the germline). The acquired response is said to be "adaptive" because it prepares the body's immune system for future challenges (though it can actually also be maladaptive when it results in autoimmunity).The system is highly adaptable because of somatic hypermutation (a process of accelerated somatic mutations), and V(D)J recombination (an irreversible genetic recombination of antigen receptor gene segments). This mechanism allows a small number of genes to generate a vast number of different antigen receptors, which are then uniquely expressed on each individual lymphocyte. Because the gene rearrangement leads to an irreversible change in the DNA of each cell, all of the progeny (offspring) of that cell will then inherit genes encoding the same receptor specificity, including the Memory B cells and Memory T cells that are the keys to long-lived specific immunity.A theoretical framework explaining the workings of the acquired immune system is provided by immune network theory. This theory, which builds on established concepts of clonal selection, is being applied in the search for an HIV vaccine.".
- Adaptive_immune_system thumbnail SEM_Lymphocyte.jpg?width=300.
- Adaptive_immune_system wikiPageExternalLink www.modelingimmunity.org.
- Adaptive_immune_system wikiPageID "1664060".
- Adaptive_immune_system wikiPageRevisionID "603828410".
- Adaptive_immune_system hasPhotoCollection Adaptive_immune_system.
- Adaptive_immune_system subject Category:Immune_system.
- Adaptive_immune_system comment "The adaptive immune system, also known as the acquired immune system or, more rarely, as the specific immune system, is a subsystem of the overall immune system that is composed of highly specialized, systemic cells and processes that eliminate or prevent pathogen growth.".
- Adaptive_immune_system label "Adaptive immune system".
- Adaptive_immune_system label "Immunità adattativa".
- Adaptive_immune_system label "Odpowiedź odpornościowa swoista".
- Adaptive_immune_system label "Sistema imune adaptativo".
- Adaptive_immune_system label "Système immunitaire adaptatif".
- Adaptive_immune_system label "Приобретённый иммунитет".
- Adaptive_immune_system label "جهاز مناعي تكيفي".
- Adaptive_immune_system label "后天免疫系统".
- Adaptive_immune_system sameAs Oroimen_immunologiko.
- Adaptive_immune_system sameAs Système_immunitaire_adaptatif.
- Adaptive_immune_system sameAs Sistem_kekebalan_tiruan.
- Adaptive_immune_system sameAs Immunità_adattativa.
- Adaptive_immune_system sameAs Odpowiedź_odpornościowa_swoista.
- Adaptive_immune_system sameAs Sistema_imune_adaptativo.
- Adaptive_immune_system sameAs m.025rygt.
- Adaptive_immune_system sameAs Q1645075.
- Adaptive_immune_system sameAs Q1645075.
- Adaptive_immune_system wasDerivedFrom Adaptive_immune_system?oldid=603828410.
- Adaptive_immune_system depiction SEM_Lymphocyte.jpg.
- Adaptive_immune_system isPrimaryTopicOf Adaptive_immune_system.
