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- Addiction_module abstract "Addiction modules are toxin-antitoxin systems. Each consists of a pair of genes that specify two components: a stable toxin and an unstable antitoxin that interferes with the lethal action of the toxin. Found first in E. coli on low copy number plasmids, addiction modules are responsible for a process called the postsegregational killing effect. When bacteria lose these plasmid(s) (or other extrachromosomal elements), the cured cells are selectively killed because the unstable antitoxin is degraded faster than the more stable toxin. The term "addiction" is used because the cell depends on the de novo synthesis of the antitoxin for cell survival. Thus, addiction modules are implicated in maintaining the stability of extrachromosomal elements.".
- Addiction_module thumbnail CcdAB_Toxin-Antitoxin_System.png?width=300.
- Addiction_module wikiPageExternalLink annurev.micro.53.1.43.
- Addiction_module wikiPageExternalLink 1528.pdf.
- Addiction_module wikiPageExternalLink ncb836.html.
- Addiction_module wikiPageID "10323278".
- Addiction_module wikiPageRevisionID "598340466".
- Addiction_module hasPhotoCollection Addiction_module.
- Addiction_module subject Category:Bacteriology.
- Addiction_module comment "Addiction modules are toxin-antitoxin systems. Each consists of a pair of genes that specify two components: a stable toxin and an unstable antitoxin that interferes with the lethal action of the toxin. Found first in E. coli on low copy number plasmids, addiction modules are responsible for a process called the postsegregational killing effect.".
- Addiction_module label "Addiction module".
- Addiction_module sameAs m.02q8gjx.
- Addiction_module sameAs Q4681115.
- Addiction_module sameAs Q4681115.
- Addiction_module wasDerivedFrom Addiction_module?oldid=598340466.
- Addiction_module depiction CcdAB_Toxin-Antitoxin_System.png.
- Addiction_module isPrimaryTopicOf Addiction_module.