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- Alfaxalone abstract "Alfaxalone (INN, also known as alphaxalone or alphaxolone) is a neurosteroid general anaesthetic.It is one of the constituents of althesin.It is used in veterinary practice under the tradename Alfaxan.It is licensed for use in both dogs and cats.[citation needed]Unlike some of its predecessors alfaxalone is not associated with histamine release and anaphylaxis.[citation needed]A study 1987 found the primary mechanism for the anaesthetic action of alfaxalone to be modulation of neuronal cell membrane chloride ion transport, induced by binding of alfaxalone to GABAA cell surface receptors.A 1994 study found that alfaxalone binds to a different region of this receptor than the benzodiazepines.Alfaxalone is metabolised rapidly in the liver. Alfaxalone has a very short plasma elimination half-life in dogs and cats.[citation needed]".
- Alfaxalone atcPrefix "N01".
- Alfaxalone atcSuffix "AX05".
- Alfaxalone casNumber "23930-19-0".
- Alfaxalone fdaUniiCode "BD07M97B2A".
- Alfaxalone iupacName "3-hydroxypregnane-11,20-dione".
- Alfaxalone pubchem "104845".
- Alfaxalone thumbnail Alphaxolone.svg?width=300.
- Alfaxalone wikiPageID "12790823".
- Alfaxalone wikiPageRevisionID "544915129".
- Alfaxalone atcPrefix "N01".
- Alfaxalone atcSuffix "AX05".
- Alfaxalone bioavailability "The alfaxalone molecule is solubilised in the Alfaxan formulation using 2α- hydroxypropyl β cyclodextrin. Cyclodextrins are complex polysaccharides derived from starch that supply a hydrophobic centre for lipophilic drugs like alfaxalone.".
- Alfaxalone c "21".
- Alfaxalone casNumber "23930".
- Alfaxalone chembl "190279".
- Alfaxalone chemspiderid "94637".
- Alfaxalone h "32".
- Alfaxalone hasPhotoCollection Alfaxalone.
- Alfaxalone inchi "1".
- Alfaxalone inchikey "DUHUCHOQIDJXAT-OLVMNOGEBO".
- Alfaxalone iupacName "3".
- Alfaxalone kegg "D07282".
- Alfaxalone molecularWeight "332.477".
- Alfaxalone o "3".
- Alfaxalone pubchem "104845".
- Alfaxalone smiles "O=C2[C@H]3[C@H]CC[C@H]4C[C@H]CC[C@]34C".
- Alfaxalone stdinchi "1".
- Alfaxalone stdinchikey "DUHUCHOQIDJXAT-OLVMNOGESA-N".
- Alfaxalone unii "BD07M97B2A".
- Alfaxalone verifiedfields "changed".
- Alfaxalone verifiedrevid "477317167".
- Alfaxalone subject Category:Alcohols.
- Alfaxalone subject Category:General_anesthetics.
- Alfaxalone subject Category:Ketones.
- Alfaxalone subject Category:Neurosteroids.
- Alfaxalone type Abstraction100002137.
- Alfaxalone type Agent114778436.
- Alfaxalone type Alcohol107884567.
- Alfaxalone type Alcohols.
- Alfaxalone type Beverage107881800.
- Alfaxalone type CausalAgent100007347.
- Alfaxalone type Chemical114806838.
- Alfaxalone type Compound114818238.
- Alfaxalone type Drug103247620.
- Alfaxalone type DrugOfAbuse103248958.
- Alfaxalone type Fluid114939900.
- Alfaxalone type Food100021265.
- Alfaxalone type Ketone114926294.
- Alfaxalone type Ketones.
- Alfaxalone type Liquid114940386.
- Alfaxalone type Material114580897.
- Alfaxalone type Matter100020827.
- Alfaxalone type OrganicCompound114727670.
- Alfaxalone type Part113809207.
- Alfaxalone type PhysicalEntity100001930.
- Alfaxalone type Relation100031921.
- Alfaxalone type Substance100019613.
- Alfaxalone type Substance100020090.
- Alfaxalone type Drug.
- Alfaxalone type DrugProduct.
- Alfaxalone type FunctionalSubstance.
- Alfaxalone comment "Alfaxalone (INN, also known as alphaxalone or alphaxolone) is a neurosteroid general anaesthetic.It is one of the constituents of althesin.It is used in veterinary practice under the tradename Alfaxan.It is licensed for use in both dogs and cats.[citation needed]Unlike some of its predecessors alfaxalone is not associated with histamine release and anaphylaxis.[citation needed]A study 1987 found the primary mechanism for the anaesthetic action of alfaxalone to be modulation of neuronal cell membrane chloride ion transport, induced by binding of alfaxalone to GABAA cell surface receptors.A 1994 study found that alfaxalone binds to a different region of this receptor than the benzodiazepines.Alfaxalone is metabolised rapidly in the liver. ".
- Alfaxalone label "Alfaxalona".
- Alfaxalone label "Alfaxalone".
- Alfaxalone label "Alfaxalone".
- Alfaxalone sameAs Alfaxalone.
- Alfaxalone sameAs Alfaxalona.
- Alfaxalone sameAs m.02x51_2.
- Alfaxalone sameAs Q3611058.
- Alfaxalone sameAs Q3611058.
- Alfaxalone sameAs Alfaxalone.
- Alfaxalone wasDerivedFrom Alfaxalone?oldid=544915129.
- Alfaxalone depiction Alphaxolone.svg.
- Alfaxalone isPrimaryTopicOf Alfaxalone.