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- Alfred_Jost abstract "Alfred Jost (1916–1991) was a French endocrinologist, famous for his discovery of the Mullerian inhibitor, now called anti-Mullerian hormone (AMH) or Mullerian inhibiting substance (MIS). Alfred Jost resolved the controversy surrounding the mechanism of somatic sex differentiation by proving that male characteristics must be imposed on the fetus by the testicular hormones testosterone and AMH, respectively responsible for the virilization of the Wolffian ducts, urogenital sinus and external genitalia and for the regression of Mullerian ducts. In the absence or inactivity of these hormones, the fetus becomes phenotypically female. Alfred Jost was also a pioneer through his work on testicular differentiation, in collaboration with Solange Magre. He was the first to show that testicular organization is heralded by the development of pre-Sertoli cells, which progressively surround germ cells to form seminiferous tubules. Alfred Jost did not rely only on his brilliant mind. He distrusted theories built on suboptimal experimental data and believed that intelligence was powerless without technical skill. His search for elegant, effective techniques led him to apply surgical methods to fetal endocrinology. He was also a fascinating teacher, particularly for pre-doctoral students.".
- Alfred_Jost birthDate "1916-07-27".
- Alfred_Jost birthPlace Strasbourg.
- Alfred_Jost birthYear "1916".
- Alfred_Jost deathDate "1991-02-03".
- Alfred_Jost deathYear "1991".
- Alfred_Jost field Endocrinology.
- Alfred_Jost knownFor Anti-M%C3%BCllerian_hormone.
- Alfred_Jost nationality French_people.
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- Alfred_Jost birthDate "1916-07-27".
- Alfred_Jost birthPlace Strasbourg.
- Alfred_Jost caption "Alfred Jost".
- Alfred_Jost dateOfBirth "1916-07-27".
- Alfred_Jost dateOfDeath "1991-02-03".
- Alfred_Jost deathDate "1991-02-03".
- Alfred_Jost field Endocrinology.
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- Alfred_Jost name "Alfred Jost".
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- Alfred_Jost placeOfBirth Strasbourg.
- Alfred_Jost shortDescription "French endocrinologist".
- Alfred_Jost workInstitutions Collège_de_France.
- Alfred_Jost description "French endocrinologist".
- Alfred_Jost description "French endocrinologist".
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- Alfred_Jost comment "Alfred Jost (1916–1991) was a French endocrinologist, famous for his discovery of the Mullerian inhibitor, now called anti-Mullerian hormone (AMH) or Mullerian inhibiting substance (MIS).".
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