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- Alrestatin abstract "Alrestatin is an inhibitor of aldose reductase, an enzyme involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.Alrestat was first synthesized in 1969 and was the first aldose reductase inhibitor (ARI) with oral bioavailability to undergo clinical trials, in the late 1970s and early 1980s. Low-quality trials and a high incidence of adverse effects (particularly hepatotoxicity) led to termination of its development, and it was never in clinical use. It is structurally related to tolrestat, another ARI that was briefly marketed before being withdrawn in 1997.".
- Alrestatin iupacName "(1,3-dioxo-1H-benzo[de]isoquinolin-2(3H)-yl)acetic acid".
- Alrestatin thumbnail Alrestatin.svg?width=300.
- Alrestatin wikiPageID "37278273".
- Alrestatin wikiPageRevisionID "590550324".
- Alrestatin hasPhotoCollection Alrestatin.
- Alrestatin imagefile "Alrestatin.svg".
- Alrestatin imagesize "160".
- Alrestatin iupacname "acetic acid".
- Alrestatin subject Category:Diabetes.
- Alrestatin type ChemicalCompound.
- Alrestatin type ChemicalSubstance.
- Alrestatin type ChemicalObject.
- Alrestatin type Thing.
- Alrestatin comment "Alrestatin is an inhibitor of aldose reductase, an enzyme involved in the pathogenesis of complications of diabetes mellitus, including diabetic neuropathy.Alrestat was first synthesized in 1969 and was the first aldose reductase inhibitor (ARI) with oral bioavailability to undergo clinical trials, in the late 1970s and early 1980s. Low-quality trials and a high incidence of adverse effects (particularly hepatotoxicity) led to termination of its development, and it was never in clinical use.".
- Alrestatin label "Alrestatin".
- Alrestatin sameAs m.0n5x4hh.
- Alrestatin sameAs Q4735714.
- Alrestatin sameAs Q4735714.
- Alrestatin wasDerivedFrom Alrestatin?oldid=590550324.
- Alrestatin depiction Alrestatin.svg.
- Alrestatin isPrimaryTopicOf Alrestatin.
