Matches in DBpedia 2014 for { <http://dbpedia.org/resource/Amidase> ?p ?o. }
Showing items 1 to 52 of
52
with 100 items per page.
- Amidase abstract "In enzymology, an amidase (EC 3.5.1.4, acylamidase, acylase (misleading), amidohydrolase (ambiguous), deaminase (ambiguous), fatty acylamidase, N-acetylaminohydrolase (ambiguous)) is an enzyme that catalyzes the hydrolysis of an amide: Thus, the two substrates of this enzyme are monocarboxylic acid amide and H2O, whereas its two products are monocarboxylate and NH3.This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. The systematic name of this enzyme class is acylamide amidohydrolase. Other names in common use include acylamidase, acylase, amidohydrolase, deaminase, fatty acylamidase, and N-acetylaminohydrolase. This enzyme participates in 6 metabolic pathways: urea cycle and metabolism of amino groups, phenylalanine metabolism, tryptophan metabolism, cyanoamino acid metabolism, benzoate degradation via coa ligation, and styrene degradation. Amidases contain a conserved stretch of approximately 130 amino acids known as the AS sequence. They are widespread, being found in both prokaryotes and eukaryotes. AS enzymes catalyse the hydrolysis of amide bonds (CO-NH2), although the family has diverged widely with regard to substrate specificity and function. Nonetheless, these enzymes maintain a core alpha/beta/alpha structure, where the topologies of the N- and C-terminal halves are similar. AS enzymes characteristically have a highly conserved C-terminal region rich in serine and glycine residues, but devoid of aspartic acid and histidine residues, therefore they differ from classical serine hydrolases. These enzymes possess a unique, highly conserved Ser-Ser-Lys catalytic triad used for amide hydrolysis, although the catalytic mechanism for acyl-enzyme intermediate formation can differ between enzymes.Examples of AS signature-containing enzymes include:Peptide amidase (Pam), which catalyses the hydrolysis of the C-terminal amide bond of peptides. Fatty acid amide hydrolases, which hydrolyse fatty acid amid substrates (e.g. cannabinoid anandamide and sleep-inducing oleamide), thereby controlling the level and duration of signalling induced by this diverse class of lipid transmitters. Malonamidase E2, which catalyses the hydrolysis of malonamate into malonate and ammonia, and which is involved in the transport of fixed nitrogen from bacteroids to plant cells in symbiotic nitrogen metabolism. Subunit A of Glu-tRNA(Gln) amidotransferase,a heterotrimeric enzyme that catalyses the formation of Gln-tRNA(Gln) by the transamidation of misacylated Glu-tRNA(Gln) via amidolysis of glutamine.↑ 1.0 1.1 ↑ ↑ ↑".
- Amidase ecNumber "3.5.1.4".
- Amidase thumbnail PDB_1m22_EBI.jpg?width=300.
- Amidase wikiPageID "14501996".
- Amidase wikiPageRevisionID "590558780".
- Amidase caption "x-ray structure of native peptide amidase from stenotrophomonas maltophilia at 1.4 a".
- Amidase casNumber "9012".
- Amidase ecNumber "3.5".
- Amidase goCode "4040".
- Amidase hasPhotoCollection Amidase.
- Amidase interpro "IPR000120".
- Amidase iubmbEcNumber "3".
- Amidase name "Amidase".
- Amidase name "amidase".
- Amidase opmFamily "72".
- Amidase opmProtein "1".
- Amidase pfam "PF01425".
- Amidase prosite "PDOC00494".
- Amidase scop "1".
- Amidase symbol "Amidase".
- Amidase subject Category:Enzymes_of_known_structure.
- Amidase subject Category:Hydrolases_acting_on_nonpeptide_C-N_bonds.
- Amidase subject Category:Protein_families.
- Amidase type Abstraction100002137.
- Amidase type Family108078020.
- Amidase type Group100031264.
- Amidase type Organization108008335.
- Amidase type ProteinFamilies.
- Amidase type SocialGroup107950920.
- Amidase type Unit108189659.
- Amidase type YagoLegalActor.
- Amidase type YagoLegalActorGeo.
- Amidase type YagoPermanentlyLocatedEntity.
- Amidase type Biomolecule.
- Amidase type Enzyme.
- Amidase type BiologicalObject.
- Amidase comment "In enzymology, an amidase (EC 3.5.1.4, acylamidase, acylase (misleading), amidohydrolase (ambiguous), deaminase (ambiguous), fatty acylamidase, N-acetylaminohydrolase (ambiguous)) is an enzyme that catalyzes the hydrolysis of an amide: Thus, the two substrates of this enzyme are monocarboxylic acid amide and H2O, whereas its two products are monocarboxylate and NH3.This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amides. ".
- Amidase label "Amidase".
- Amidase label "Amidasen".
- Amidase label "Amidasi".
- Amidase label "アミダーゼ".
- Amidase sameAs Amidasen.
- Amidase sameAs Amidasi.
- Amidase sameAs アミダーゼ.
- Amidase sameAs m.03d5j5n.
- Amidase sameAs Q408149.
- Amidase sameAs Q408149.
- Amidase sameAs Amidase.
- Amidase wasDerivedFrom Amidase?oldid=590558780.
- Amidase depiction PDB_1m22_EBI.jpg.
- Amidase isPrimaryTopicOf Amidase.
- Amidase name "amidase".
