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- Amrinone abstract "Amrinone (INN) or inamrinone (USAN, changed in 2000 to prevent confusion with amiodarone), trade name Inocor, is a pyridine phosphodiesterase 3 inhibitor. It is a drug that may improve the prognosis in patients with congestive heart failure. Amrinone has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR). The positive inotropic effect of amrinone is mediated by the selective enhancement of high gain CICR which contributes to the contraction of myocytes by phosphorylation through cAMP dependent protein kinase A (PKA) and Ca2+ calmodulin kinase pathways.".
- Amrinone atcPrefix "C01".
- Amrinone atcSuffix "CE01".
- Amrinone casNumber "60719-84-8".
- Amrinone drugbank "DB01427".
- Amrinone fdaUniiCode "JUT23379TN".
- Amrinone iupacName "5-amino-3,4'-bipyridin-6(1H)-one".
- Amrinone pubchem "3698".
- Amrinone thumbnail Amrinone.svg?width=300.
- Amrinone wikiPageID "6833822".
- Amrinone wikiPageRevisionID "590583175".
- Amrinone atcPrefix "1.0".
- Amrinone atcSuffix "CE01".
- Amrinone bioavailability "n/a".
- Amrinone c "10".
- Amrinone casNumber "60719".
- Amrinone chembl "12856".
- Amrinone chemspiderid "3570".
- Amrinone drugbank "DB01427".
- Amrinone eliminationHalfLife "28800.0".
- Amrinone excretion "Renal and fecal".
- Amrinone h "9".
- Amrinone hasPhotoCollection Amrinone.
- Amrinone inchi "1".
- Amrinone inchikey "RNLQIBCLLYYYFJ-UHFFFAOYAR".
- Amrinone iupacName "5".
- Amrinone kegg "D00231".
- Amrinone legalUs "Rx-only".
- Amrinone metabolism Liver.
- Amrinone molecularWeight "187.198".
- Amrinone n "3".
- Amrinone o "1".
- Amrinone pregnancyUs "C".
- Amrinone proteinBound "10".
- Amrinone pubchem "3698".
- Amrinone routesOfAdministration Intravenous_therapy.
- Amrinone smiles "O=C2C=C\C=C/N2".
- Amrinone stdinchi "1".
- Amrinone stdinchikey "RNLQIBCLLYYYFJ-UHFFFAOYSA-N".
- Amrinone unii "JUT23379TN".
- Amrinone verifiedrevid "443387938".
- Amrinone subject Category:2-Pyridones.
- Amrinone subject Category:Aromatic_amines.
- Amrinone subject Category:Cardiac_stimulants.
- Amrinone subject Category:Inotropic_agents.
- Amrinone subject Category:PDE3_inhibitors.
- Amrinone subject Category:Pyridines.
- Amrinone subject Category:Vasodilators.
- Amrinone type Drug.
- Amrinone type DrugProduct.
- Amrinone type FunctionalSubstance.
- Amrinone comment "Amrinone (INN) or inamrinone (USAN, changed in 2000 to prevent confusion with amiodarone), trade name Inocor, is a pyridine phosphodiesterase 3 inhibitor. It is a drug that may improve the prognosis in patients with congestive heart failure. Amrinone has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release (CICR).".
- Amrinone label "Amrinon".
- Amrinone label "Amrinone".
- Amrinone label "Anrinona".
- Amrinone label "アムリノン".
- Amrinone sameAs Amrinon.
- Amrinone sameAs アムリノン.
- Amrinone sameAs Anrinona.
- Amrinone sameAs m.0grnqc.
- Amrinone sameAs Q422724.
- Amrinone sameAs Q422724.
- Amrinone sameAs DB01427.
- Amrinone sameAs 3698.
- Amrinone wasDerivedFrom Amrinone?oldid=590583175.
- Amrinone depiction Amrinone.svg.
- Amrinone isPrimaryTopicOf Amrinone.