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- Ancestim abstract "Ancestim is a recombinant methionyl human stem cell factor, branded by Amgen as StemGen. It was developed by Amgen and sold to Biovitrium, now Swedish Orphan Biovitrum, in December, 2008.It is a 166 amino acid protein produced by E. coli bacteria into which a gene has been inserted for soluble human stem cell factor. It has a monomeric molecular weight of approximately 18,500 daltons and normally exists as a noncovalently associated dimer. The protein has an amino acid sequence that is identical to the natural sequence predicted from human DNA sequence analysis, except for the addition of an N-terminal methionine retained after expression in E. coli. Because Ancestim is produced in E. coli, it is nonglycosylated. Ancestim is supplied as a sterile, white, preservative-free, lyophilised powder for reconstitution and administration as a subcutaneous (SC) injection and is indicated for use in combination with filgrastim for mobilizing peripheral hematopoietic stem cells for later transplanation in certain cancer patients.".
- Ancestim atcPrefix "L03".
- Ancestim atcSuffix "AA12".
- Ancestim casNumber "163545-26-4".
- Ancestim fdaUniiCode "PYB4Q6JG41".
- Ancestim wikiPageID "11462963".
- Ancestim wikiPageRevisionID "588295578".
- Ancestim atcPrefix "L03".
- Ancestim atcSuffix "AA12".
- Ancestim casNumber "163545".
- Ancestim chemspiderid "NA".
- Ancestim eliminationHalfLife "9000.0".
- Ancestim excretion "renal: 90%".
- Ancestim hasPhotoCollection Ancestim.
- Ancestim kegg "D02937".
- Ancestim routesOfAdministration "s.c. injection only, premedication with H1 and H2 antihistamines and beta-receptor agonists for bronchodilation".
- Ancestim unii "PYB4Q6JG41".
- Ancestim verifiedfields "changed".
- Ancestim verifiedrevid "457130070".
- Ancestim subject Category:Proteins.
- Ancestim type Abstraction100002137.
- Ancestim type Chemical114806838.
- Ancestim type Compound114818238.
- Ancestim type Macromolecule114944888.
- Ancestim type Material114580897.
- Ancestim type Matter100020827.
- Ancestim type Molecule114682133.
- Ancestim type OrganicCompound114727670.
- Ancestim type Part113809207.
- Ancestim type PhysicalEntity100001930.
- Ancestim type Protein114728724.
- Ancestim type Proteins.
- Ancestim type Relation100031921.
- Ancestim type Substance100019613.
- Ancestim type Thing100002452.
- Ancestim type Unit109465459.
- Ancestim type Drug.
- Ancestim type DrugProduct.
- Ancestim type FunctionalSubstance.
- Ancestim comment "Ancestim is a recombinant methionyl human stem cell factor, branded by Amgen as StemGen. It was developed by Amgen and sold to Biovitrium, now Swedish Orphan Biovitrum, in December, 2008.It is a 166 amino acid protein produced by E. coli bacteria into which a gene has been inserted for soluble human stem cell factor. It has a monomeric molecular weight of approximately 18,500 daltons and normally exists as a noncovalently associated dimer.".
- Ancestim label "Ancestim".
- Ancestim sameAs m.02rdn84.
- Ancestim sameAs Q4752549.
- Ancestim sameAs Q4752549.
- Ancestim sameAs Ancestim.
- Ancestim wasDerivedFrom Ancestim?oldid=588295578.
- Ancestim isPrimaryTopicOf Ancestim.