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- Arthropod_defensin abstract "Arthropod defensins are a family of insect and scorpion cysteine-rich antibacterial peptides, primarily active against Gram-positive bacteria. All these peptides range in length from 38 to 51 amino acids. There are six conserved cysteines all involved in intrachain disulfide bonds. The role of these highly conserved cysteines is not known. Studies have shown that disulfide bonds are not required for antimicrobial activity.[1] Mammalian defensins also do not require disulfide bonds to exhibit antimicrobial activity. [2] Furthermore, it was also shown that the N-terminal helix region in arthropod or insect defensins is also not required for antimicrobial activity of these peptides.[3]A schematic representation of peptides from the arthropod defensin family is shown below. +----------------------------+ | | xxCxxxxxxxxxxxxxxCxxxCxxxxxxxxxCxxxxxCxCxx | | | | +---|---------------+ | +-----------------+'C': conserved cysteine involved in a disulfide bond.Although low level sequence similarities have been reported between the arthropod defensins and mammalian defensins, the topological arrangement of the disulfide bonds as well as the tertiary structure are completely different in the two families.".
- Arthropod_defensin symbol "Defensin_2".
- Arthropod_defensin thumbnail PDB_1ica_EBI.jpg?width=300.
- Arthropod_defensin wikiPageExternalLink 4561.short.
- Arthropod_defensin wikiPageExternalLink S019697810600310X.
- Arthropod_defensin wikiPageID "14846529".
- Arthropod_defensin wikiPageRevisionID "605302901".
- Arthropod_defensin caption "Structure of insect defensin A.".
- Arthropod_defensin hasPhotoCollection Arthropod_defensin.
- Arthropod_defensin interpro "IPR001542".
- Arthropod_defensin name "Arthropod defensin".
- Arthropod_defensin opmFamily "61".
- Arthropod_defensin opmProtein "1".
- Arthropod_defensin pfam "PF01097".
- Arthropod_defensin prosite "PDOC00356".
- Arthropod_defensin scop "1".
- Arthropod_defensin symbol "Defensin_2".
- Arthropod_defensin tcdb "1".
- Arthropod_defensin subject Category:Insect_immunity.
- Arthropod_defensin subject Category:Peripheral_membrane_proteins.
- Arthropod_defensin subject Category:Protein_domains.
- Arthropod_defensin subject Category:Toxins.
- Arthropod_defensin type Abstraction100002137.
- Arthropod_defensin type Attribute100024264.
- Arthropod_defensin type Chemical114806838.
- Arthropod_defensin type Compound114818238.
- Arthropod_defensin type Environment113934596.
- Arthropod_defensin type Macromolecule114944888.
- Arthropod_defensin type Material114580897.
- Arthropod_defensin type Matter100020827.
- Arthropod_defensin type Molecule114682133.
- Arthropod_defensin type OrganicCompound114727670.
- Arthropod_defensin type Part113809207.
- Arthropod_defensin type PeripheralMembraneProteins.
- Arthropod_defensin type PhysicalEntity100001930.
- Arthropod_defensin type Protein114728724.
- Arthropod_defensin type ProteinDomains.
- Arthropod_defensin type Relation100031921.
- Arthropod_defensin type Situation113927383.
- Arthropod_defensin type Sphere114514039.
- Arthropod_defensin type State100024720.
- Arthropod_defensin type Substance100019613.
- Arthropod_defensin type Thing100002452.
- Arthropod_defensin type Unit109465459.
- Arthropod_defensin type Biomolecule.
- Arthropod_defensin type Protein.
- Arthropod_defensin type BiologicalObject.
- Arthropod_defensin comment "Arthropod defensins are a family of insect and scorpion cysteine-rich antibacterial peptides, primarily active against Gram-positive bacteria. All these peptides range in length from 38 to 51 amino acids. There are six conserved cysteines all involved in intrachain disulfide bonds. The role of these highly conserved cysteines is not known.".
- Arthropod_defensin label "Arthropod defensin".
- Arthropod_defensin sameAs m.03gzygg.
- Arthropod_defensin sameAs Q4797673.
- Arthropod_defensin sameAs Q4797673.
- Arthropod_defensin sameAs Arthropod_defensin.
- Arthropod_defensin wasDerivedFrom Arthropod_defensin?oldid=605302901.
- Arthropod_defensin depiction PDB_1ica_EBI.jpg.
- Arthropod_defensin isPrimaryTopicOf Arthropod_defensin.
