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- BD1008 abstract "BD1008 or N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-1-pyrrolidineethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 2 ± 1 nM for the sigma-1 receptor and 4 times selectivity over the sigma-2 receptor.Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with BD1008 significantly attenuates the behavioral toxicity of cocaine, and may be potentially useful in the development of antidotes for the treatment of cocaine overdose.".
- BD1008 casNumber "138356-08-8".
- BD1008 iupacName "N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-1-pyrrolidineethanamine".
- BD1008 thumbnail BD1008.png?width=300.
- BD1008 wikiPageID "36175312".
- BD1008 wikiPageRevisionID "587300822".
- BD1008 c "15".
- BD1008 casNumber "138356".
- BD1008 cl "2".
- BD1008 h "22".
- BD1008 hasPhotoCollection BD1008.
- BD1008 iupacName "N-[2-ethyl]-N-methyl-1-pyrrolidineethanamine".
- BD1008 molecularWeight "301.25".
- BD1008 n "2".
- BD1008 subject Category:Organochlorides.
- BD1008 subject Category:Pyrrolidines.
- BD1008 type Drug.
- BD1008 type FunctionalSubstance.
- BD1008 comment "BD1008 or N-[2-(3,4-dichlorophenyl)ethyl]-N-methyl-1-pyrrolidineethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 2 ± 1 nM for the sigma-1 receptor and 4 times selectivity over the sigma-2 receptor.Consistent with other reported sigma receptor antagonists, pretreating Swiss Webster mice with BD1008 significantly attenuates the behavioral toxicity of cocaine, and may be potentially useful in the development of antidotes for the treatment of cocaine overdose.".
- BD1008 label "BD1008".
- BD1008 sameAs m.0ch1wy3.
- BD1008 sameAs Q12744660.
- BD1008 sameAs Q12744660.
- BD1008 wasDerivedFrom BD1008?oldid=587300822.
- BD1008 depiction BD1008.png.
- BD1008 isPrimaryTopicOf BD1008.
