Matches in DBpedia 2014 for { <http://dbpedia.org/resource/BIN1> ?p ?o. }
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- BIN1 abstract "Myc box-dependent-interacting protein 1 is a protein that in humans is encoded by the BIN1 gene.This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.".
- BIN1 entrezgene "274".
- BIN1 wikiPageID "14132500".
- BIN1 wikiPageRevisionID "603584605".
- BIN1 hasPhotoCollection BIN1.
- BIN1 requireManualInspection "no".
- BIN1 summaryText "This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.".
- BIN1 updateCitations "yes".
- BIN1 updatePage "yes".
- BIN1 updateProteinBox "yes".
- BIN1 updateSummary "yes".
- BIN1 type Biomolecule.
- BIN1 type Protein.
- BIN1 type BiologicalObject.
- BIN1 comment "Myc box-dependent-interacting protein 1 is a protein that in humans is encoded by the BIN1 gene.This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin.".
- BIN1 label "BIN1".
- BIN1 label "BIN1".
- BIN1 sameAs BIN1.
- BIN1 sameAs m.03cvlfp.
- BIN1 sameAs Q4835693.
- BIN1 sameAs Q4835693.
- BIN1 wasDerivedFrom BIN1?oldid=603584605.
- BIN1 isPrimaryTopicOf BIN1.