Matches in DBpedia 2014 for { <http://dbpedia.org/resource/BUB3> ?p ?o. }
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- BUB3 abstract "Mitotic checkpoint protein BUB3 is a protein that in humans is encoded by the BUB3 gene.Bub3 is a protein involved with the regulation of the Spindle Assembly Checkpoint (SAC); though BUB3 is non-essential in yeast, it is essential in higher eukaryotes. As one of the checkpoint proteins, Bub3 delays the irreversible onset of anaphase through direction of kinetochore localization during prometaphase to achieve biorentation. In directing the kinetochore-microtubule interaction, this ensures the proper (and consequenctly, bioriented) attachment of the chromosomes prior to anaphase. Bub3 and its related proteins that form the Spindle Assembly Checkpoint (SAC) inhibit the action of the Anaphase Promoting Complex (APC), preventing early anaphase entry and mitotic exit; this serves as a mechanism for the fidelity of chromosomal segregation.".
- BUB3 entrezgene "9184".
- BUB3 wikiPageID "14798224".
- BUB3 wikiPageRevisionID "599610241".
- BUB3 hasPhotoCollection BUB3.
- BUB3 type Biomolecule.
- BUB3 type Protein.
- BUB3 type BiologicalObject.
- BUB3 comment "Mitotic checkpoint protein BUB3 is a protein that in humans is encoded by the BUB3 gene.Bub3 is a protein involved with the regulation of the Spindle Assembly Checkpoint (SAC); though BUB3 is non-essential in yeast, it is essential in higher eukaryotes. As one of the checkpoint proteins, Bub3 delays the irreversible onset of anaphase through direction of kinetochore localization during prometaphase to achieve biorentation.".
- BUB3 label "BUB3".
- BUB3 sameAs BUB3.
- BUB3 sameAs m.03gyb8s.
- BUB3 sameAs Q4836785.
- BUB3 sameAs Q4836785.
- BUB3 sameAs 5534.
- BUB3 wasDerivedFrom BUB3?oldid=599610241.
- BUB3 isPrimaryTopicOf BUB3.