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- BYSL abstract "Bystin is a protein that in humans is encoded by the BYSL gene.Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi.".
- BYSL entrezgene "705".
- BYSL wikiPageID "14811706".
- BYSL wikiPageRevisionID "590839140".
- BYSL hasPhotoCollection BYSL.
- BYSL requireManualInspection "no".
- BYSL summaryText "Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present. Immunocytochemistry of HT-H cells showed that bystin colocalizes with trophinin, tastin, and the cytokeratins, suggesting that these molecules form a complex in trophectoderm cells at the time of implantation. Using immunohistochemistry it was determined that trophinin and bystin are found in the placenta from the sixth week of pregnancy. Both proteins were localized in the cytoplasm of the syncytiotrophoblast in the chorionic villi and in endometrial decidual cells at the uteroplacental interface. After week 10, the levels of trophinin, tastin, and bystin decreased and then disappeared from placental villi.".
- BYSL updateCitations "yes".
- BYSL updatePage "yes".
- BYSL updateProteinBox "yes".
- BYSL updateSummary "yes".
- BYSL type Biomolecule.
- BYSL type Protein.
- BYSL type BiologicalObject.
- BYSL comment "Bystin is a protein that in humans is encoded by the BYSL gene.Bystin is expressed as a 2-kb major transcript and a 3.6-kb minor transcript in SNG-M cells and in human trophoblastic teratocarcinoma HT-H cells. Protein binding assays determined that bystin binds directly to trophinin and tastin, and that binding is enhanced when cytokeratins 8 and 18 are present.".
- BYSL label "BYSL".
- BYSL sameAs m.03gyqlf.
- BYSL sameAs Q4836880.
- BYSL sameAs Q4836880.
- BYSL wasDerivedFrom BYSL?oldid=590839140.
- BYSL isPrimaryTopicOf BYSL.