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- BZIP_Maf abstract "bZIP Maf is a domain found in Maf transcription factor proteins. It contains a leucine zipper (bZIP) domain, which mediates the transcription factor's dimerization and DNA binding properties. The Maf extended homology region (EHR) is present at the N-terminus of the protein. This region (shown in yellow in the image to the right) exists only within the Maf family and allows the family to recognize longer DNA motifs than other leucine zippers. These motifs are termed the Maf recognition element (MARE) and is 13 or 14 base pairs long. In particular, the two residues at the beginning of helix H2 are positioned to recognise the flanking region of the DNA. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF2-E2 transcription factor.In mouse, Maf1 may play an early role in axial patterning. Defects in these proteins are a cause of autosomal dominant retinitis pigmentosa. Neural retina-specific leucine zipper proteins belong to this family.".
- BZIP_Maf symbol "bZIP_Maf".
- BZIP_Maf thumbnail Crystal_structure_of_the_MafA_homodimer.png?width=300.
- BZIP_Maf wikiPageID "32172190".
- BZIP_Maf wikiPageRevisionID "590839606".
- BZIP_Maf caption "Crystal structure of the MafA homodimer bound to DNA. PDB entry".
- BZIP_Maf hasPhotoCollection BZIP_Maf.
- BZIP_Maf interpro "IPR004826".
- BZIP_Maf name "bZIP_Maf".
- BZIP_Maf pfam "PF03131".
- BZIP_Maf pfamClan "CL0018".
- BZIP_Maf scop "1".
- BZIP_Maf symbol "bZIP_Maf".
- BZIP_Maf subject Category:Protein_families.
- BZIP_Maf type Abstraction100002137.
- BZIP_Maf type Family108078020.
- BZIP_Maf type Group100031264.
- BZIP_Maf type Organization108008335.
- BZIP_Maf type ProteinFamilies.
- BZIP_Maf type SocialGroup107950920.
- BZIP_Maf type Unit108189659.
- BZIP_Maf type YagoLegalActor.
- BZIP_Maf type YagoLegalActorGeo.
- BZIP_Maf type YagoPermanentlyLocatedEntity.
- BZIP_Maf type Biomolecule.
- BZIP_Maf type Protein.
- BZIP_Maf type BiologicalObject.
- BZIP_Maf comment "bZIP Maf is a domain found in Maf transcription factor proteins. It contains a leucine zipper (bZIP) domain, which mediates the transcription factor's dimerization and DNA binding properties. The Maf extended homology region (EHR) is present at the N-terminus of the protein. This region (shown in yellow in the image to the right) exists only within the Maf family and allows the family to recognize longer DNA motifs than other leucine zippers.".
- BZIP_Maf label "BZIP Maf".
- BZIP_Maf sameAs m.0gw_t02.
- BZIP_Maf sameAs Q4836925.
- BZIP_Maf sameAs Q4836925.
- BZIP_Maf sameAs BZIP_Maf.
- BZIP_Maf wasDerivedFrom BZIP_Maf?oldid=590839606.
- BZIP_Maf depiction Crystal_structure_of_the_MafA_homodimer.png.
- BZIP_Maf isPrimaryTopicOf BZIP_Maf.
