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- Basiliximab abstract "Basiliximab (trade name Simulect) is a chimeric mouse-human monoclonal antibody to the α chain (CD25) of the IL-2 receptor of T cells. It is used to prevent rejection in organ transplantation, especially in kidney transplants. It is a Novartis Pharmaceuticals product and was approved by the Food and Drug Administration (FDA) in 1998.It is a chimeric CD25 monoclonal antibody of the IgG1 isotype. It acts as an antagonist at the interleukin-2(IL-2) binding site of the p55 subunit (Tac antigen) of the high affinity IL-2 receptor (CD25) on the surface of the activated T lymphocytes.Minimum serum level should be 0.2 ug/ml(ELISA)Dose is 20 mg two times 4 days apart generally in an adult. It is given in two doses, the first within 2 hours of the start of the transplant operation and the second 4 days after the transplant. These saturate the receptors and prevent T cells from replication and also from activating the B cells, which are responsible for the production of antibodies, which would bind to the transplanted organ and stimulate an immune response against the transplant.Like the similar drug daclizumab, basiliximab reduces the incidence and severity of acute rejection in kidney transplantation without increasing the incidence of opportunistic infections.[citation needed] In the United Kingdom, the National Institute for Health and Clinical Excellence has recommended its use be considered for all kidney transplant recipients.It has been reported that some cases of Lichen Planus have been successfully treated with Basiliximab as an alternative therapy to Cyclosporine, with a dose of 20 mg every 4 days. No short-term side effects have been reported".
- Basiliximab atcPrefix "L04".
- Basiliximab atcSuffix "AC02".
- Basiliximab casNumber "152923-56-3".
- Basiliximab drugbank "DB00074".
- Basiliximab fdaUniiCode "9927MT646M".
- Basiliximab wikiPageID "530538".
- Basiliximab wikiPageRevisionID "587246745".
- Basiliximab atcPrefix "L04".
- Basiliximab atcSuffix "AC02".
- Basiliximab c "6378".
- Basiliximab casNumber "152923".
- Basiliximab chembl "1201439".
- Basiliximab chemspiderid "NA".
- Basiliximab drugbank "DB00074".
- Basiliximab eliminationHalfLife "622080.0".
- Basiliximab h "9844".
- Basiliximab hasPhotoCollection Basiliximab.
- Basiliximab mabType "mab".
- Basiliximab molecularWeight "143801.3".
- Basiliximab n "1698".
- Basiliximab o "1997".
- Basiliximab pregnancyUs "B".
- Basiliximab s "48".
- Basiliximab source "xi/o".
- Basiliximab target CD25.
- Basiliximab tradename "Simulect".
- Basiliximab type "mab".
- Basiliximab unii "9927".
- Basiliximab verifiedfields "changed".
- Basiliximab verifiedrevid "459525440".
- Basiliximab width "220".
- Basiliximab subject Category:Immunosuppressants.
- Basiliximab type Agent114778436.
- Basiliximab type CausalAgent100007347.
- Basiliximab type Drug103247620.
- Basiliximab type Immunosuppressant103562958.
- Basiliximab type Immunosuppressants.
- Basiliximab type Matter100020827.
- Basiliximab type Medicine103740161.
- Basiliximab type PhysicalEntity100001930.
- Basiliximab type Substance100020090.
- Basiliximab type Drug.
- Basiliximab type DrugProduct.
- Basiliximab type FunctionalSubstance.
- Basiliximab comment "Basiliximab (trade name Simulect) is a chimeric mouse-human monoclonal antibody to the α chain (CD25) of the IL-2 receptor of T cells. It is used to prevent rejection in organ transplantation, especially in kidney transplants. It is a Novartis Pharmaceuticals product and was approved by the Food and Drug Administration (FDA) in 1998.It is a chimeric CD25 monoclonal antibody of the IgG1 isotype.".
- Basiliximab label "Basiliximab".
- Basiliximab label "Basiliximab".
- Basiliximab label "Basiliximab".
- Basiliximab label "Basiliximab".
- Basiliximab label "Bazyliksymab".
- Basiliximab label "Базиликсимаб".
- Basiliximab label "باسيليكسيماب".
- Basiliximab sameAs Basiliximab.
- Basiliximab sameAs Basiliximab.
- Basiliximab sameAs Basiliximab.
- Basiliximab sameAs Bazyliksymab.
- Basiliximab sameAs m.02m3pf.
- Basiliximab sameAs Q418702.
- Basiliximab sameAs Q418702.
- Basiliximab sameAs basiliximab.
- Basiliximab sameAs DB00074.
- Basiliximab sameAs Basiliximab.
- Basiliximab wasDerivedFrom Basiliximab?oldid=587246745.
- Basiliximab isPrimaryTopicOf Basiliximab.