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- Biginelli_reaction abstract "The Biginelli reaction is a multiple-component chemical reaction that creates 3,4-dihydropyrimidin-2(1H)-ones 4 from ethyl acetoacetate 1, an aryl aldehyde (such as benzaldehyde 2), and urea 3. It is named for the Italian chemist Pietro Biginelli.This reaction was developed by Pietro Biginelli in 1891. The reaction can be catalyzed by Brønsted acids and/or by Lewis acids such as copper(II) trifluoroacetate hydrate and boron trifluoride. Several solid-phase protocols utilizing different linker combinations have been published.Dihydropyrimidinones, the products of the Biginelli reaction, are widely used in the pharmaceutical industry as calcium channel blockers, antihypertensive agents, and alpha-1-a-antagonists.".
- Biginelli_reaction thumbnail Biginelli_Reaction_Scheme.png?width=300.
- Biginelli_reaction wikiPageID "2728910".
- Biginelli_reaction wikiPageRevisionID "606337736".
- Biginelli_reaction hasPhotoCollection Biginelli_reaction.
- Biginelli_reaction subject Category:Carbon-carbon_bond_forming_reactions.
- Biginelli_reaction subject Category:Condensation_reactions.
- Biginelli_reaction subject Category:Multiple_component_reactions.
- Biginelli_reaction subject Category:Name_reactions.
- Biginelli_reaction type ChemicalProcess113446390.
- Biginelli_reaction type ChemicalReaction113447361.
- Biginelli_reaction type CondensationReactions.
- Biginelli_reaction type MultipleComponentReactions.
- Biginelli_reaction type NameReactions.
- Biginelli_reaction type NaturalProcess113518963.
- Biginelli_reaction type PhysicalEntity100001930.
- Biginelli_reaction type Process100029677.
- Biginelli_reaction comment "The Biginelli reaction is a multiple-component chemical reaction that creates 3,4-dihydropyrimidin-2(1H)-ones 4 from ethyl acetoacetate 1, an aryl aldehyde (such as benzaldehyde 2), and urea 3. It is named for the Italian chemist Pietro Biginelli.This reaction was developed by Pietro Biginelli in 1891. The reaction can be catalyzed by Brønsted acids and/or by Lewis acids such as copper(II) trifluoroacetate hydrate and boron trifluoride.".
- Biginelli_reaction label "Biginelli reaction".
- Biginelli_reaction label "Biginelli-Reaktion".
- Biginelli_reaction label "Biginelli-reactie".
- Biginelli_reaction label "Réaction de Biginelli".
- Biginelli_reaction label "Síntesis de pirimidina de Biginelli".
- Biginelli_reaction label "ビギネリ反応".
- Biginelli_reaction label "比吉内利反应".
- Biginelli_reaction sameAs Biginelli-Reaktion.
- Biginelli_reaction sameAs Síntesis_de_pirimidina_de_Biginelli.
- Biginelli_reaction sameAs Réaction_de_Biginelli.
- Biginelli_reaction sameAs ビギネリ反応.
- Biginelli_reaction sameAs Biginelli-reactie.
- Biginelli_reaction sameAs m.07_dwx.
- Biginelli_reaction sameAs Q859694.
- Biginelli_reaction sameAs Q859694.
- Biginelli_reaction sameAs Biginelli_reaction.
- Biginelli_reaction wasDerivedFrom Biginelli_reaction?oldid=606337736.
- Biginelli_reaction depiction Biginelli_Reaction_Scheme.png.
- Biginelli_reaction isPrimaryTopicOf Biginelli_reaction.
