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- Bisulfite_sequencing abstract "Bisulphite sequencing (also known as bisulfite sequencing) is the use of bisulphite treatment of DNA to determine its pattern of methylation. DNA methylation was the first discovered epigenetic mark, and remains the most studied. In animals it predominantly involves the addition of a methyl group to the carbon-5 position of cytosine residues of the dinucleotide CpG, and is implicated in repression of transcriptional activity.Treatment of DNA with bisulphite converts cytosine residues to uracil, but leaves 5-methylcytosine residues unaffected. Thus, bisulphite treatment introduces specific changes in the DNA sequence that depend on the methylation status of individual cytosine residues, yielding single- nucleotide resolution information about the methylation status of a segment of DNA. Various analyses can be performed on the altered sequence to retrieve this information. The objective of this analysis is therefore reduced to differentiating between single nucleotide polymorphisms (cytosines and thymidine) resulting from bisulphite conversion (Figure 1).".
- Bisulfite_sequencing thumbnail Wiki_Bisulfite_sequencing_Figure_1_small.png?width=300.
- Bisulfite_sequencing wikiPageExternalLink bs-seq-and-beyond.
- Bisulfite_sequencing wikiPageExternalLink index.php.
- Bisulfite_sequencing wikiPageExternalLink www.epigenome.org.
- Bisulfite_sequencing wikiPageExternalLink protocols.shtml.htm.
- Bisulfite_sequencing wikiPageExternalLink epigenome.
- Bisulfite_sequencing wikiPageExternalLink Bisulfite-conversion-and-MSP-Protocol.
- Bisulfite_sequencing wikiPageID "9773858".
- Bisulfite_sequencing wikiPageRevisionID "590796175".
- Bisulfite_sequencing hasPhotoCollection Bisulfite_sequencing.
- Bisulfite_sequencing subject Category:Epigenetics.
- Bisulfite_sequencing subject Category:Genomics.
- Bisulfite_sequencing subject Category:Molecular_biology.
- Bisulfite_sequencing comment "Bisulphite sequencing (also known as bisulfite sequencing) is the use of bisulphite treatment of DNA to determine its pattern of methylation. DNA methylation was the first discovered epigenetic mark, and remains the most studied.".
- Bisulfite_sequencing label "Bisulfite sequencing".
- Bisulfite_sequencing label "Бисульфитное секвенирование".
- Bisulfite_sequencing label "亞硫酸鹽定序".
- Bisulfite_sequencing sameAs Bisulfit-Sequenzierung.
- Bisulfite_sequencing sameAs m.02prstx.
- Bisulfite_sequencing sameAs Q4087270.
- Bisulfite_sequencing sameAs Q4087270.
- Bisulfite_sequencing wasDerivedFrom Bisulfite_sequencing?oldid=590796175.
- Bisulfite_sequencing depiction Wiki_Bisulfite_sequencing_Figure_1_small.png.
- Bisulfite_sequencing isPrimaryTopicOf Bisulfite_sequencing.
