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- Boronic_acid abstract "A boronic acid is an alkyl or aryl substituted boric acid containing a carbon–boron bond belonging to the larger class of organoboranes. Boronic acids act as Lewis acids. Their unique feature is that they are capable of forming reversible covalent complexes with sugars, amino acids, hydroxamic acids, etc. (molecules with vicinal, (1,2) or occasionally (1,3) substituted Lewis base donors (alcohol, amine, carboxylate)). The pKa of a boronic acid is ~9, but they can form tetrahedral boronate complexes with pKa ~7. They are occasionally used in the area of molecular recognition to bind to saccharides for fluorescent detection or selective transport of saccharides across membranes.Boronic acids are used extensively in organic chemistry as chemical building blocks and intermediates predominantly in the Suzuki coupling. A key concept in its chemistry is transmetallation of its organic residue to a transition metal.The compound bortezomib with a boronic acid group is a drug used in chemotherapy. The boron atom in this molecule is a key substructure because through it certain proteasomes are blocked that would otherwise degrade proteins.".
- Boronic_acid thumbnail Boronic-acid-2D.png?width=300.
- Boronic_acid wikiPageExternalLink www.organoborons.com.
- Boronic_acid wikiPageID "7114058".
- Boronic_acid wikiPageRevisionID "583055330".
- Boronic_acid hasPhotoCollection Boronic_acid.
- Boronic_acid subject Category:Boronic_acids.
- Boronic_acid subject Category:Functional_groups.
- Boronic_acid type Abstraction100002137.
- Boronic_acid type Acid114607521.
- Boronic_acid type BoronicAcids.
- Boronic_acid type Chemical114806838.
- Boronic_acid type Compound114818238.
- Boronic_acid type FunctionalGroups.
- Boronic_acid type Group100031264.
- Boronic_acid type Material114580897.
- Boronic_acid type Matter100020827.
- Boronic_acid type Part113809207.
- Boronic_acid type PhysicalEntity100001930.
- Boronic_acid type Relation100031921.
- Boronic_acid type Substance100019613.
- Boronic_acid comment "A boronic acid is an alkyl or aryl substituted boric acid containing a carbon–boron bond belonging to the larger class of organoboranes. Boronic acids act as Lewis acids. Their unique feature is that they are capable of forming reversible covalent complexes with sugars, amino acids, hydroxamic acids, etc. (molecules with vicinal, (1,2) or occasionally (1,3) substituted Lewis base donors (alcohol, amine, carboxylate)).".
- Boronic_acid label "Acide boronique".
- Boronic_acid label "Acido boronico".
- Boronic_acid label "Boronic acid".
- Boronic_acid label "Boronsäuren".
- Boronic_acid label "Ácido borónico".
- Boronic_acid label "ボロン酸".
- Boronic_acid sameAs Boronsäuren.
- Boronic_acid sameAs Ácido_borónico.
- Boronic_acid sameAs Acide_boronique.
- Boronic_acid sameAs Acido_boronico.
- Boronic_acid sameAs ボロン酸.
- Boronic_acid sameAs m.0h4v58.
- Boronic_acid sameAs Q335768.
- Boronic_acid sameAs Q335768.
- Boronic_acid sameAs Boronic_acid.
- Boronic_acid wasDerivedFrom Boronic_acid?oldid=583055330.
- Boronic_acid depiction Boronic-acid-2D.png.
- Boronic_acid isPrimaryTopicOf Boronic_acid.
