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- Brattleboro_rat abstract "The Brattleboro rat is a strain of laboratory rat descended from a litter born in West Brattleboro, Vermont in 1961 without the ability to produce the hormone vasopressin, which helps control kidney function. The rats' lack of vasopressin was the result of a naturally occurring genetic mutation.The rats were being raised for laboratory use by Dr. Henry Schroeder and technician Tim Vinton, who noticed that the litter of 17 drank and urinated excessively. The researchers determined that the rats failed to produce vasopressin, an antidiuretic hormone, and they gave the rats to Dartmouth Medical School (DMS). Researchers there determined that the rats had a mutation in the gene that regulates the production of vasopressin.The DMS researchers bred the rats for distribution to scientists around the world to use in testing the possible role of vasopressin in any given biological function. The Brattleboro rat was an early and naturally occurring precursor of the knockout rat.".
- Brattleboro_rat wikiPageExternalLink 4di_brattleboro_rat.htm.
- Brattleboro_rat wikiPageID "13481566".
- Brattleboro_rat wikiPageRevisionID "538672157".
- Brattleboro_rat hasPhotoCollection Brattleboro_rat.
- Brattleboro_rat subject Category:Model_organisms.
- Brattleboro_rat subject Category:Rats.
- Brattleboro_rat type LivingThing100004258.
- Brattleboro_rat type ModelOrganisms.
- Brattleboro_rat type Object100002684.
- Brattleboro_rat type Organism100004475.
- Brattleboro_rat type PhysicalEntity100001930.
- Brattleboro_rat type Whole100003553.
- Brattleboro_rat comment "The Brattleboro rat is a strain of laboratory rat descended from a litter born in West Brattleboro, Vermont in 1961 without the ability to produce the hormone vasopressin, which helps control kidney function. The rats' lack of vasopressin was the result of a naturally occurring genetic mutation.The rats were being raised for laboratory use by Dr. Henry Schroeder and technician Tim Vinton, who noticed that the litter of 17 drank and urinated excessively.".
- Brattleboro_rat label "Brattleboro rat".
- Brattleboro_rat sameAs m.03c6syn.
- Brattleboro_rat sameAs Q4958126.
- Brattleboro_rat sameAs Q4958126.
- Brattleboro_rat sameAs Brattleboro_rat.
- Brattleboro_rat wasDerivedFrom Brattleboro_rat?oldid=538672157.
- Brattleboro_rat isPrimaryTopicOf Brattleboro_rat.