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- Bronchial_challenge_test abstract "A bronchial challenge test is a medical test used to assist in the diagnosis of asthma. The patient breathes in nebulized methacholine or histamine. Thus the test may also be called a methacholine challenge test or histamine challenge test respectively. Both drugs provoke bronchoconstriction, or narrowing of the airways. Whereas histamine causes nasal and bronchial mucus secretion and bronchoconstriction via the H1 receptor, methacholine utilizes the M3 receptor for bronchoconstriction. The degree of narrowing can then be quantified by spirometry. People with pre-existing airway hyperreactivity, such as asthmatics, will react to lower doses of drug.Sometimes, to assess the reversibility of a particular condition, a bronchodilator is administered to counteract the effects of the bronchoconstrictor before repeating the spirometry tests. This is commonly referred to as a reversibility test, or a post bronchodilator test (post BD), and may help in distinguishing asthma from chronic obstructive pulmonary disease.False positives and negatives are possible in the bronchial challenge test. In addition, asthma may be temporary due to an exposure to noxious stimuli or exercise.The bronchial challenge test is physically demanding, and the results can be affected by muscular weakness or exhaustion. The inhaled drug can stimulate the upper airway sufficiently to cause violent coughing. This can make spirometry difficult or impossible. This test is contraindicated in patients with severe airway obstruction due to the obvious worsening of the obstruction.".
- Bronchial_challenge_test wikiPageID "13923750".
- Bronchial_challenge_test wikiPageRevisionID "590814927".
- Bronchial_challenge_test hasPhotoCollection Bronchial_challenge_test.
- Bronchial_challenge_test name "Bronchial challenge test".
- Bronchial_challenge_test subject Category:Medical_tests.
- Bronchial_challenge_test subject Category:Respiratory_system_procedures.
- Bronchial_challenge_test type Abstraction100002137.
- Bronchial_challenge_test type Act100030358.
- Bronchial_challenge_test type Activity100407535.
- Bronchial_challenge_test type Cognition100023271.
- Bronchial_challenge_test type Event100029378.
- Bronchial_challenge_test type Experiment105798043.
- Bronchial_challenge_test type HigherCognitiveProcess105770664.
- Bronchial_challenge_test type Inquiry105797597.
- Bronchial_challenge_test type MedicalTests.
- Bronchial_challenge_test type ProblemSolving105796750.
- Bronchial_challenge_test type Procedure101023820.
- Bronchial_challenge_test type Process105701363.
- Bronchial_challenge_test type PsychologicalFeature100023100.
- Bronchial_challenge_test type RespiratorySystemProcedures.
- Bronchial_challenge_test type Thinking105770926.
- Bronchial_challenge_test type Trial105799212.
- Bronchial_challenge_test type YagoPermanentlyLocatedEntity.
- Bronchial_challenge_test comment "A bronchial challenge test is a medical test used to assist in the diagnosis of asthma. The patient breathes in nebulized methacholine or histamine. Thus the test may also be called a methacholine challenge test or histamine challenge test respectively. Both drugs provoke bronchoconstriction, or narrowing of the airways. Whereas histamine causes nasal and bronchial mucus secretion and bronchoconstriction via the H1 receptor, methacholine utilizes the M3 receptor for bronchoconstriction.".
- Bronchial_challenge_test label "Bronchial challenge test".
- Bronchial_challenge_test label "Methacholintest".
- Bronchial_challenge_test label "Spirometryczna próba prowokacyjna".
- Bronchial_challenge_test sameAs Methacholintest.
- Bronchial_challenge_test sameAs Spirometryczna_próba_prowokacyjna.
- Bronchial_challenge_test sameAs Prova_de_broncoprovocação.
- Bronchial_challenge_test sameAs m.03cnbfv.
- Bronchial_challenge_test sameAs Q1925324.
- Bronchial_challenge_test sameAs Q1925324.
- Bronchial_challenge_test sameAs Bronchial_challenge_test.
- Bronchial_challenge_test wasDerivedFrom Bronchial_challenge_test?oldid=590814927.
- Bronchial_challenge_test isPrimaryTopicOf Bronchial_challenge_test.